Over 12 years, 1092 patients underwent 2019 craniomaxillofacial procedures in Toronto. Overall mortality was 0.64 percent, and that directly related to surgery was 0.18 percent. Major complications developed in 14.3 percent of patients, but not all had permanent sequelae. Infection was the greatest problem, occurring in 5.3 percent of the major operations. The annual incidence of complications dropped to 5.4 percent as our experience increased. Certain types of deformity, particularly those in patients with orbital hypertelorism, Treacher-Collins syndrome, or Crouzon's or Apert's syndrome, require more than one operation to achieve maximum correction. Our procedures have undergone many changes, the main one being a reduced operating time.
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http://dx.doi.org/10.1097/00006534-198507000-00005 | DOI Listing |
Cureus
December 2024
Obstetrics and Gynecology, F. Edward Hebert School of Medicine, Uniformed Services University, Bethesda, USA.
Background: Depending upon their organization and content, medical conferences can enhance wellness or create additional stress for physician attendees. The objective of our study was to examine the degree to which major medical specialty and subspecialty conferences incorporate wellness into their meeting programs.
Methods: We performed a cross-sectional study of major medical conferences occurring in 2023 representing specialties and subspecialties with the greatest number of active physicians.
Drug Metab Dispos
January 2025
Global Clinical Development, Chiesi Farmaceutici SpA, Parma, Italy.
Tanimilast is an inhaled phosphodiesterase-4 inhibitor currently in phase III clinical development for treating chronic obstructive pulmonary disease and asthma. This trial aimed to characterize the pharmacokinetics, mass balance, and metabolite profiling of tanimilast. Eight healthy male volunteers received a single dose of nonradiolabeled tanimilast via powder inhaler (Chiesi NEXThaler [3200 μg]), followed by a concomitant intravenous infusion of a microtracer ([C]-tanimilast: 18.
View Article and Find Full Text PDFJ Vasc Surg
January 2025
Baylor University Medical Center, Department of Anesthesia, Division of Anesthesia.
Introduction: Thoracic outlet syndrome (TOS) encompasses multiple symptoms produced by compression of the neurovascular bundle within the thoracic outlet. The subtypes of thoracic outlet are termed for the major affected structure including neurogenic (nTOS), venous (vTOS), and arterial (aTOS) thoracic outlet syndrome. Neurogenic thoracic outlet syndrome accounts for over 95 percent of thoracic outlet syndrome cases and occurs from compression of the brachial plexus.
View Article and Find Full Text PDFSouth Med J
February 2025
the Department of Public Health Sciences.
Objectives: Sickle cell disease (SCD), which disproportionately affects minorities, increases complications during pregnancy. Severe maternal mortality is increased in women with SCD, including morbidity related to the disease and other nondisease-related complications. It also can have devastating complications for fetuses, with increases in premature birth and low birth weight.
View Article and Find Full Text PDFPublic Health Nutr
January 2025
School of Life Sciences, Arizona State University, Tempe, AZ, USA.
Objective: While fast-food is typically considered highly processed, an analysis to demonstrate this has yet to be conducted. Therefore, the objective of this research was to examine the menu items and ingredients from six fast-food restaurant menus using the NOVA Classification.
Design: Cross-sectional study.
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