AI Article Synopsis
- Acute ethanol intake in overnight-fasted rats led to higher levels of lipid peroxides in the liver, indicating increased oxidative stress.
- The liver's glutathione content, an important antioxidant, was found to be reduced after ethanol administration.
- Despite these changes, the activity of glutathione peroxidase enzymes stayed the same, while the activity of glutathione transferase enzymes dropped.
Article Abstract
Acute ethanol administration to rats fasted overnight resulted in increased lipid peroxide levels and decreased glutathione content in the liver. In this condition, hepatic glutathione peroxidase activity remained unchanged, whereas glutathione transferase activity was decreased.
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| http://dx.doi.org/10.1016/0031-6989(85)90098-0 | DOI Listing |
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