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Evaluating the influence of anti-PD-1 immunotherapy combined with IMRT on thyroid dysfunction in nasopharyngeal carcinoma.
Front Immunol
January 2025
The Second Clinical Medical College of Jinan University, Department of Radiotherapy, Shenzhen People's Hospital, Shenzhen, Guangdong, China.
Background: Immunotherapy represents a major breakthrough in malignant tumor treatment in recent years. Anti-PD-1 immunotherapy has significantly prolonged Event-free Survival (EFS) in Nasopharyngeal Carcinoma (NPC). However, its potent anti-tumor effects can also attack normal tissues and organs, leading to immune-related adverse effects (irAE), with the thyroid being one of the most commonly affected organs.
View Article and Find Full Text PDFPostoperative and permanent hypocalcemia after indocyanine green (ICG) angiography-guided total thyroidectomy and central neck dissection: A retrospective cohort study.
Surgery
January 2025
Service of Digestive and General Surgery, Hospital Universitario de La Princesa, Instituto de Investigación Sanitaria Princesa (IIS-IP), Universidad Autónoma de Madrid (UAM), Madrid, Spain.
Background: This study aimed to compare the rates of postoperative and permanent hypocalcemia between postthyroidectomy indocyanine green angiography and indocyanine green angiography-guided thyroidectomy performed intraoperatively for identification and preservation of the parathyroids.
Methods: We undertook a retrospective study of 2 cohorts of patients with thyroid cancer undergoing total thyroidectomy and central neck dissection. The first cohort (control group) included patients who underwent postthyroidectomy indocyanine green angiography to predict parathyroid function by scoring the degree of fluorescence (0, black; nonvascularized; 1, gray/heterogeneous: partially vascularized; and 2, white: well vascularized), and the second cohort (angiography-guided thyroidectomy) included patients undergoing initially indocyanine green angiography-guided thyroidectomy to identify the feeding vessels of the parathyroid glands followed by postthyroidectomy indocyanine green angiography.
Fascial Forearm Free Flap for Large Tracheal Defect Closure.
JAMA Otolaryngol Head Neck Surg
January 2025
Department of Otolaryngology-Head and Neck Surgery, University Hospital of Modena, Modena, Italy.
Primary Leiomyosarcoma of the Thyroid.
Head Neck Pathol
January 2025
Department of medical oncology, Habib Bourguiba Hospital, University of Sfax, Sfax, 3029, Tunisia.
Leiomyosarcoma (LMS) is a malignant mesenchymal neoplasm showing smooth muscle differentiation. Primary LMS of the thyroid gland is quite rare, accounting for only 0.014% of cases.
View Article and Find Full Text PDFCorrection: Immune checkpoint inhibitors-related thyroid dysfunction: influencing factor analysis, prediction model development, and management strategy proposal.
Cancer Immunol Immunother
January 2025
Department of Pharmacy, Peking University Third Hospital, Beijing, 100191, China.
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