Diatoms are among the most diverse and ecologically significant groups of photosynthetic microalgae, contributing over 20% of global primary productivity. Their ecological significance, unique biology, and genetic tractability make them ideal targets for genetic and genomic engineering and metabolic reprogramming. Over the past few decades, numerous genetic methods have been developed and applied to these organisms to better understand the function of individual genes and how they underpin diatom metabolism. Additionally, the ability of diatoms to synthesize diverse high-value metabolites and elaborate mineral structures offers significant potential for applications in biotechnology, including the synthesis of novel pharmaceuticals, nutraceuticals, and biomaterials. This review discusses the latest developments in diatom genetic engineering and provides prospects not only to promote the use of diatoms in diverse fields of biotechnology but also to deepen our understanding of their role in natural ecosystems.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/tpj.70102 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Spatial distribution and activation changes of T cells in pancreatic tumors according to KRAS mutation subtype.
Cancer Lett
March 2025
Department of Biochemistry and Molecular Biology, University of Ulsan College of Medicine, Asan Medical Center, Seoul 05505, Republic of Korea; Department of Convergence Medicine, Asan Medical Center, Seoul 05505, Republic of Korea; Asan Preclinical Evaluation Center for Cancer Therapeutix, Asan Medical Center, Seoul 05505, Republic of Korea; Division of Hepato-Biliary and Pancreatic Surgery, Department of Surgery, University of Ulsan College of Medicine, Asan Medical Center, Seoul 05505, Republic of Korea. Electronic address:
To enhance immunotherapy efficacy in pancreatic cancer, it is crucial to characterize its immune landscape and identify key factors driving immune alterations. To achieve this, we quantitatively analyzed the immune microenvironment using multiplex immunohistochemistry, assessing the spatial relationships between immune and tumor cells to correlate with patient survival rates and oncological factors. Additionally, through Whole Exome Sequencing analysis based on public data, we explored genetic mutations that could drive these compositions.
View Article and Find Full Text PDFAnaerobic digestion at hyper-mesophilic temperatures: Microbiome and antibiotic resistome in full-scale agricultural biogas plants.
J Hazard Mater
March 2025
Centre for Environmental Health and Engineering (CEHE), School of Engineering, University of Surrey, Guildford GU2 7XH, United Kingdom. Electronic address:
Temperatures between 40°C and 50°C are increasingly implemented in full-scale agricultural anaerobic digestion (AD), yet the microbial diversity and antibiotic resistome dynamics within this temperature range remain poorly understood. Here, we defined this range as "hyper-mesophilic" and surveyed five full-scale sites. Significant differences were found in the bacterial community structure, potentially stemming from feedstock combination (high vs low/non-manure) and operating temperature.
View Article and Find Full Text PDFDynamics of ammonia-oxidizing microorganisms in gradient temperature-regulated reactors under low ammonia loading condition.
J Environ Manage
March 2025
Department of Environmental and Sustainable Engineering, Faculty of Engineering, Chulalongkorn University, Bangkok, Thailand; Biotechnology for Wastewater Engineering Research Unit, Chulalongkorn University, Bangkok, Thailand. Electronic address:
Ammonia-oxidizing microorganisms (AOMs) play a crucial role in nitrogen removal in engineered systems. However, temperature fluctuations can lead to ammonia oxidation failure. This study investigated the effects of a broad temperature range (10.
View Article and Find Full Text PDFGenome-wide characterization of pepper DREB family members and biological function of CaDREB32 in response to salt and osmotic stresses.
Plant Physiol Biochem
March 2025
The Engineering Research Institute of Agriculture and Forestry, Ludong University, 264025, Yantai, Shandong Province, China; College of Horticulture, Ludong University, 264025, Yantai, Shandong Province, China; Yantai Technology Center of Characteristic Plant Gene Editing and Germplasm Innovation, Ludong University, 264025, Yantai, Shandong Province, China; Zhaoyuan Shenghui Agricultural Technology Development Co., Ltd, 265400, Zhaoyuan, Shandong Province, China. Electronic address:
Dehydration response element binding (DREB) transcription factors play multiple roles in plant growth, development and response to abiotic stress. However, their biological functions in response to salt and osmotic stress in vegetables of the Solanaceae family are largely unclear. Here, 49 CaDREB genes classified into six groups were identified in the pepper genome.
View Article and Find Full Text PDFDecoding genetic diversity through genome engineering in bryophytes.
Plant J
March 2025
Shenzhen Branch, Guangdong Laboratory for Lingnan Modern Agriculture, Shenzhen Key Laboratory of Agricultural Synthetic Biology, Genome Analysis Laboratory of the Ministry of Agriculture and Rural Affairs, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen, 518124, China.
Bryophytes, which include mosses, liverworts, and hornworts, have evolved a highly successful strategy for thriving in terrestrial environments, allowing them to occupy nearly every land ecosystem. Their success is due to a unique combination of biochemical adaptations, diverse structural forms, and specialized life cycle strategies. The key to their evolutionary success lies in their genomic diversity.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!