A PHP Error was encountered

Severity: Warning

Message: fopen(/var/lib/php/sessions/ci_session4s3vlt0rkb9kmkbubef2lutgfs5viukv): Failed to open stream: No space left on device

Filename: drivers/Session_files_driver.php

Line Number: 177

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once

A PHP Error was encountered

Severity: Warning

Message: session_start(): Failed to read session data: user (path: /var/lib/php/sessions)

Filename: Session/Session.php

Line Number: 137

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once

A PHP Error was encountered

Severity: Warning

Message: file_get_contents(https://...@gmail.com&api_key=61f08fa0b96a73de8c900d749fcb997acc09&a=1): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests

Filename: helpers/my_audit_helper.php

Line Number: 197

Backtrace:

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 197
Function: file_get_contents

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 271
Function: simplexml_load_file_from_url

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3145
Function: getPubMedXML

File: /var/www/html/application/controllers/Detail.php
Line: 575
Function: pubMedSearch_Global

File: /var/www/html/application/controllers/Detail.php
Line: 489
Function: pubMedGetRelatedKeyword

File: /var/www/html/index.php
Line: 316
Function: require_once

Multivitamin Use and Mammographic Breast Density. | LitMetric

Multivitamin Use and Mammographic Breast Density.

J Nutr

Division of Public Health Sciences, Department of Surgery, Washington University School of Medicine, St. Louis, MO, United States; Siteman Cancer Center, Washington University School of Medicine, St. Louis, MO, United States. Electronic address:

Published: March 2025

Purpose: The association of multivitamin use with mammographic breast density (MBD) is unclear, with two studies reporting conflicting findings. We, therefore, investigated the associations of multivitamin use with volumetric measures of MBD; volumetric percent density (VPD), dense volume (DV), and non-dense volume (NDV) in a diverse population of women.

Methods: This cross-sectional study included 1,083 women recruited during their annual screening mammograms at the Joanne Knight Breast Health Center, Washington University School of Medicine, St. Louis, MO. Participants were classified based on self-reported multivitamin use into non-users, <1 day/week, 1-3 days/week, 4-6 days/week, and daily users. MBD was assessed as VPD, DV, and NDV using Volpara 1.5. Data were analyzed using general linear modeling, adjusted for potential confounders, including age, BMI, race, menopausal status, education, age at menarche, family history of breast cancer, parity and age at first birth, oral contraceptive use, menopausal hormone therapy use, and alcohol intake. Statistical significance was set at p <0.05.

Results: Multivitamin use was not associated with VPD. The adjusted mean VPD was 7.0% (95% CI 6.6%-7.2%) for non-users, 7.1% (95% CI 6.4%-8.0%) for women who used multivitamins <1 day/week, 7.4% (95% CI 6.6%-8.3%) for women who used multivitamins 1-3 days/week, 7.1% (95% CI 6.3%-7.7%) for women who used multivitamins 4-6 days/week, and 6.9% (95% CI 6.6%-7.3%) for daily users (p-value= 0.794). Similar null associations were observed between multivitamin use and DV and NDV. Race and premenopausal women did not modify the associations.

Conclusions: We found no associations between multivitamin use and MBD, regardless of the frequency of use. Studies evaluating the potential interactions between dietary patterns, specific nutrients, and MBD are needed to enhance our understanding of how dietary factors impact MBD.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tjnut.2025.03.010DOI Listing

Publication Analysis

Top Keywords

multivitamin mammographic
8
mammographic breast
8
breast density
8
multivitamin
4
density purpose
4
purpose association
4
association multivitamin
4
density mbd
4
mbd unclear
4
unclear studies
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!