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Antibacterial mechanism of lysine against Escherichia coli O157:H7, its action on lettuce and in reducing the severity of murine colitis.
Food Microbiol
August 2025
College of Food Science and Engineering, Northwest A&F University, 22 Xinong Road, Yangling, 712100, Shaanxi, China. Electronic address:
The aim of the present study was to evaluate the mechanism of antimicrobial action of Lysine (Lys) against Escherichia coli (E. coli) O157:H7. Lys alters the permeability and morphology of bacterial cell membranes, leading to leakage of intracellular material.
View Article and Find Full Text PDFCombined traditional Chinese medicine and probiotics (TCMP) alleviates lipid accumulation and improves metabolism in high-fat diet mice via the microbiota-gut-liver axis.
Food Res Int
April 2025
College of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou 310058, China; Innovation Center of Yangtze River Delta, Zhejiang University, Jiaxing 314100, China. Electronic address:
Lipid accumulation and metabolic disorders caused by a high-fat diet (HFD) pose significant threats to human health, and place a substantial burden on individuals and society. In this study, a novel combination comprising three traditional Chinese herbs (lotus leaf, hawthorn, and leaf of Chinese holly) and a probiotic (Bifidobacterium lactis BPL-1) (TCMP) was prepared. Then, its effects on growth performance, fat accumulation, hepatic function and gut microbiota in mice fed a high-fat diet were investigated.
View Article and Find Full Text PDFLactic acid fermentation of a novel Sea buckthorn-monk fruit beverage: Phenolic profile, volatile compounds, and antidiabetic and antihypertensive potential.
Food Res Int
April 2025
School of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, China. Electronic address:
Functional foods offer health benefits that extend beyond basic nutrition, addressing critical public health challenges such as diabetes and hypertension. This study developed a novel lactic acid bacteria (LAB)-fermented beverage integrating sea buckthorn and monk fruit, two bioactive-rich ingredients with complementary properties. Sea buckthorn provides a robust profile of antioxidants, while monk fruit's natural sweetness and low glycemic index make it an ideal ingredient for health-conscious consumers.
View Article and Find Full Text PDFCharcot neuroarthropathy: Surgical and conservative treatment approaches.
Semin Vasc Surg
March 2025
Keck School of Medicine, University of Southern California, Los Angeles, CA.
Charcot neuroarthropathy (CN) is an inflammatory condition affecting the joints of patients with peripheral neuropathy; its prevalence is as high as 7.5%. It is commonly seen in patients with diabetes and poses a significant public health burden.
View Article and Find Full Text PDFCorrelation between changes in apathy and cognition in Alzheimer's disease associated apathy: Analysis of the Apathy in Dementia Methylphenidate Trial 2 (ADMET 2).
Int Psychogeriatr
March 2025
Sunnybrook Research Institute, University of Toronto, Toronto, ON, Canada; Department of Psychiatry, University of Toronto, Toronto, ON, Canada. Electronic address:
Background: Previous trials have shown improvements in both apathy and cognition with methylphenidate (MPH).
Objectives: To assess whether changes in apathy correlated with changes in cognition in the Apathy in Dementia Methylphenidate Trial 2 (ADMET 2).
Participants: Mild to moderate AD patients with clinically significant apathy randomized to MPH (20 mg/day) or placebo for 6 months.
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