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Psychiatric morbidities and Quality of Life Among Surgically Treated Noma Survivors. Preliminary observations in Nigerian cohorts.
J Stomatol Oral Maxillofac Surg
March 2025
Department of Dental & Maxillofacial Surgery, Federal Medical Centre, Birnin Kebbi, Nigeria. Electronic address:
Introduction: Facial disfigurement, a sequelae of Noma, has the potential to impact the mental and social well-being of survivors, predisposing them to psychiatric morbidities and low health-related quality of life (HRQoL). The aim of the study is to determine the psychiatric morbidities and QoL among Noma patients in Nigeria.
Material And Methods: A total of 41 participants were recruited and sociodemographic data were collected.
Is chitosan-based dressing more effective than gauze pressure in achieving early hemostasis after dental extractions in patients with deranged coagulation profiles?
Arch Craniofac Surg
March 2025
Oral and Maxillofacial Surgery, Oral Health Sciences Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Background: Chitosan, a cationic polysaccharide, exerts hemostatic activity by promoting platelet adhesion and aggregation. This clinical study aimed to evaluate the effectiveness of chitosan-based dental dressing in achieving early local hemostasis, in comparison to gauze packs, after dental extractions in patients with deranged coagulation profiles.
Methods: : This study included 102 patients (204 extraction sites), of whom 86 were on anticoagulant therapy,15 had liver cirrhosis, and one with thrombocytopenic purpura required two or more tooth extractions.
Implementing a Secondary Database as a Teaching Tool to Improve Genomic Literacy Among Dental Students.
Clin Teach
April 2025
Mike Petryk School of Dentistry, Faculty of Medicine & Dentistry, College of Health Sciences, University of Alberta, Alberta, Canada.
Background: Recent advancements in precision medicine and precision dentistry have necessitated genomic literacy in healthcare professionals. Both the knowledge of genetics and data in primary biological databases are rapidly expanding beyond what is presented in textbooks. Dental students are often unfamiliar with the growing field of biological data and the tools used to analyse and interpret genetic information.
View Article and Find Full Text PDFThe 5-HT Descending Facilitation System Contributes to the Disinhibition of Spinal PKCγ Neurons and Neuropathic Allodynia via 5-HT Receptors.
Neurosci Bull
March 2025
Department of Anesthesiology and Perioperative Medicine, Department of Pain Medicine, Key Laboratory of Anesthesiology, Ministry of Education of China, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, China.
Neuropathic pain, often featuring allodynia, imposes significant physical and psychological burdens on patients, with limited treatments due to unclear central mechanisms. Addressing this challenge remains a crucial unsolved issue in pain medicine. Our previous study, using protein kinase C gamma (PKCγ)-tdTomato mice, highlights the spinal feedforward inhibitory circuit involving PKCγ neurons in gating neuropathic allodynia.
View Article and Find Full Text PDFFalls among geriatric cancer patients: a systematic review and meta-analysis of prevalence and risk across cancer types.
BMC Geriatr
March 2025
South Asia Infant Feeding Research Network, Division of Evidence Synthesis, Global Consortium of Public Health and Research, Dattameghe Institute of Higher Education, Wardha, India.
Background: Falls represent a significant health concern among the older adults, particularly geriatric cancer patients, due to their increased susceptibility from both age-related and cancer treatment-related factors. This systematic review and meta-analysis aimed to synthesize global data on the prevalence and risk of falls in this population to inform targeted fall prevention strategies.
Methods: Following PRISMA 2020 guidelines, we conducted a comprehensive search of PubMed, Embase, and Web of Science up to October 2024.
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