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Multifaceted disparities exist between men and women with thoracic aortic aneurysm and dissection. Despite a higher prevalence of thoracic aortic aneurysm and dissection among men, women experience disproportionately accelerated aneurysmal expansion, greater risks of rupture or dissection, and acute aortic syndromes that occur at relatively smaller diameters. In the context of acute type A aortic dissection, they also experience more complications, increased out-of-hospital mortality, delays in presentation and diagnosis, and worse postoperative survival. These gaps are largely driven by sex differences in vascular aging and remodeling, which include arterial stiffening associated with the hormonal changes that occur during menopause. Furthermore, the increased risk of acute type A aortic dissection during pregnancy in women with thoracic aortic disease necessitates a multidisciplinary approach to peripartum counseling and surveillance. Despite significant recent improvements in early postoperative outcomes, other disparities persist, emphasizing the need for sex-specific research, patient counseling, routine monitoring, and surgical thresholds to bridge the gap in outcomes of thoracic aortic care between sexes. Elucidating the underlying mechanisms of aortic aging and its difference between men and women, as well as moving toward personalized management protocols, will give rise to improved outcomes in the treatment of thoracic aortopathy.
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http://dx.doi.org/10.1161/CIRCRESAHA.124.325681 | DOI Listing |
Ann Ital Chir
March 2025
Department of Cardiothoracic Surgery, Royal Infirmary of Edinburgh, EH16 4SA Edinburgh, UK.
Aim: Gastrointestinal (GI) complications following cardiac surgery are infrequent, but associated with high rates of postoperative mortality. The aim of our study was to identify risk factors predisposing patients to GI complications following cardiac surgery and describe the outcomes of patients suffering a GI complication.
Methods: This was a retrospective cohort study of 6769 consecutive patients undergoing cardiac surgeries (at least one of coronary artery bypass grafting (CABG), aortic valve replacement, mitral valve replacement, or surgery on thoracic aorta) at a single Scottish centre between 1 January 2015 and 27 September 2023.
J Cardiol
March 2025
Department of Cardiology, Shonan Kamakura General Hospital, Kamakura, Japan.
Background: In Japan, transcatheter aortic valve replacement (TAVR) with self-expanding valves (SEV) was approved for patients with severe aortic stenosis (AS) and on chronic maintenance dialysis in May 2023. This study assessed the safety and efficacy of TAVR with SEVs in this patient population.
Methods: This prospective, non-randomized, single-center study evaluated the safety and effectiveness of TAVR using a supra-annular SEV in Japanese patients with severe AS on chronic maintenance dialysis.
Interdiscip Cardiovasc Thorac Surg
March 2025
Department of cardiac surgery, Rennes University hospital, Rennes, France.
Objectives: This study provides a thorough analysis of cardiac surgeons' involvement in transcatheter aortic valve replacement (TAVR) activities in France, covering decision-making, procedural roles, training, and outcome analysis.
Methods: A nationwide survey was sent to all cardiac surgeons and all cardiac surgery trainees in France. Subgroup analysis was performed for age, status (established versus in-training), and type of practice facility.
Anat Histol Embryol
March 2025
Universidad San Francisco de Quito|Escuela de Medicina Veterinaria|Instituto de Biodiversidad Tropical|Hospital de Fauna Silvestre TUERI, Quito, Pichincha, Ecuador.
Persistent Fourth Right Aortic Arch (PRAA) with retention of the left ductus arteriosus constitutes the most prevalent clinically significant form of vascular ring anomalies in both dogs and cats, accounting for approximately 95% of aortic arch developmental anomalies. This anomaly causes oesophageal compression in weaned animals, leading to restricted passage of solid food, postprandial regurgitation, and potential development of acquired megaoesophagus. Notably, neonatal or lactating animals usually do not exhibit these consequences.
View Article and Find Full Text PDFEur J Vasc Endovasc Surg
March 2025
Department of Radiology, Marie Lannelongue Hospital, Groupe Hospitalier Paris Saint Joseph, Paris, France.
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