Background: This study aimed to investigate the clinical effects of bone fusion distal to the phalangeal epiphyseal plate in treating asymmetrical type III thumb polydactyly, focusing on growth and scar healing.
Methods: In patients with asymmetrical type III thumb syndactyly, the proximal phalanx of the accessory finger, distal epiphyseal plate, and some soft tissue were excised to create a pedicled tissue flap. This flap, containing part of the nail and bone distal to the epiphyseal plate, was subsequently attached to the distal segment of the main finger. The therapeutic effect was evaluated during follow-up.
Results: Ten children (6 boys and 4 girls) were included, with follow-up periods ranging from 24 to 60 months. All parents expressed satisfaction with the appearance and function of reconstructed thumbs. All reconstructed thumbs utilizing pedicled composite tissue flaps survived without arteriovenous crises, and there were no instances of perioperative mortality or wound infection. Compared with the contralateral normal thumb, most reconstructed thumbs exhibited good alignment and similar length and circumference. The reconstructed nails demonstrated a smooth surface with an appropriate curvature of the nail margin. The interphalangeal (IP) joint remained stable, and no instability of the IP joint collateral ligament was observed. The active and passive ranges of motion of the IP joint were satisfactory, and the epiphyseal plate of the reconstructed thumb was well-developed.
Conclusions: This method is considerably effective in reconstructing asymmetrical type III thumb duplication through fusion of bone distal to the phalangeal epiphyseal plate.
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http://dx.doi.org/10.1097/GOX.0000000000006545 | DOI Listing |
Regen Biomater
January 2025
Department of Orthopedics, National Children's Medical Center & Children's Hospital of Fudan University, Shanghai 201102, P. R. China.
The growth plate is crucial for skeletal growth in children, but research on repairing growth plate damage and restoring growth is limited. Here, a high-toughness adaptive dual-crosslinked hydrogel is designed to mimic the growth plate's structure, supporting regeneration and bone growth. Composed of aldehyde-modified bacterial cellulose (DBNC), methacrylated gelatin (GelMA) and sodium alginate (Alg), the hydrogel is engineered through ionic bonding and Schiff base reactions, creating a macroporous structure.
View Article and Find Full Text PDFPlast Reconstr Surg Glob Open
March 2025
From the Department of Hand and Foot, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China.
Background: This study aimed to investigate the clinical effects of bone fusion distal to the phalangeal epiphyseal plate in treating asymmetrical type III thumb polydactyly, focusing on growth and scar healing.
Methods: In patients with asymmetrical type III thumb syndactyly, the proximal phalanx of the accessory finger, distal epiphyseal plate, and some soft tissue were excised to create a pedicled tissue flap. This flap, containing part of the nail and bone distal to the epiphyseal plate, was subsequently attached to the distal segment of the main finger.
Int J Mol Sci
February 2025
Department of Hygiene, Epidemiology and Metabolic Disorders, Medical University of Bialystok, 15-089 Białystok, Poland.
Titanium is widely recognized for its biocompatibility and utility in maxillofacial and orthopedic surgery; however, its influence on bone remodeling biomarkers remains underexplored. This study investigates the effects of uncoated titanium plates on both the growth factors and diacylglycerols (DAGs) in the periostea of the maxilla and mandible, as DAG signaling is an essential secondary messenger molecule involved in intracellular signaling connected to various growth factors. The study group comprised 20 patients undergoing bimaxillary osteotomies using miniplates and screws made of Ti6Al4V titanium, from whom bone fixations were removed, while the control group included 20 patients operated on for dentofacial deformities (before the insertion of titanium fixations).
View Article and Find Full Text PDFSci Rep
March 2025
Faculty of Pharmacy, Department of Pharmacognosy, Ain Shams University, Abbassia, 11566, Cairo, Egypt.
Biofilm formation is responsible for persistent diseases related to chronic infections. Mostly it is triggered by many bacteria, mainly Pseudomonas aeruginosa (P. aeruginosa).
View Article and Find Full Text PDFInt J Surg Case Rep
March 2025
Pathology Anatomy Department, Eka Hospital, Bekasi, West Java, Indonesia.
Introduction And Importance: A terminal extensor tendon disruption, with or without bony avulsion, may lead to a mallet deformity. In most cases, trauma precedes deformity. Non-traumatic causes are less probable.
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