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Sandwich-type graphene electrochemical sensor for nucleic acid detection of SARS-CoV-2.
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Shandong Provincial Key Laboratory of Chemical Energy Storage and Novel Cell Technology, School of Chemistry and Chemical Engineering, Liaocheng University, Liaocheng 252059, China.
Nickel hydroxide has ultra-high energy storage capacity in supercapacitors, but poor electrical conductivity limits their further application. The use of graphene to improve its conductivity is an effective measure, but how to suppress the stacking of graphene and improve the overall performance of composite materials has become a new challenge. In this work, a well-designed substrate of N-doped carbon nanowires with reduced graphene oxide (NCNWs/rGO) was fabricated by growing polypyrrole (PPy) nanowires between GO nanosheets layers and then calcining them at high temperatures.
View Article and Find Full Text PDFNanocellulose-modified electrodes for simultaneous biosensing of microbiome-related oral diseases biomarkers.
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Department of Analytical Chemistry, Faculty of Chemistry, Universidad Complutense de Madrid, 28040, Madrid, Spain.
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View Article and Find Full Text PDFDevelopment of a sandwich-type electrochemical DNA sensor based on CeO/AuPt nanoprobes for highly sensitive detection of hepatitis B virus DNA.
Bioelectrochemistry
June 2025
The Key Laboratory of Biomedical Material, School of Life Science and Technology, Xinxiang Medical University, Xinxiang 453003 China. Electronic address:
To provide accurate diagnostic evidence for early hepatitis B virus (HBV) infection-related diseases, this study targeted HBV DNA as an analyte, where a sandwich-type electrochemical DNA sensor based on gold nanoparticles/reduced graphene oxide (Au NPs/ERGO) and cerium oxide/gold-platinum nanoparticles (CeO/AuPt NPs) was constructed. Au NPs/ERGO composite nanomaterials were first synthesized on the surface of a glass carbon electrode using electrochemical co-reduction, which significantly improved the specific surface area and electrical conductivity of the electrode. Further specific hybridization of target HBV-DNA was performed by combining capture probe DNA (S1-DNA) bound to AuNPs/ERGO with CeO/AuPt modified signal probe DNA (S2-DNA).
View Article and Find Full Text PDFElectrochemical biosensor based on composite of gold nanoparticle/reduced-graphene oxide/graphitic carbon nitride and a caprolactone polymer for highly sensitive detection of CEA.
Bioelectrochemistry
June 2025
Henan University of Chinese Medicine, Zhengzhou 450046, People's Republic of China.
Article Synopsis
- Carcinoembryonic antigen (CEA) is an important biomarker for diagnosing and treating diseases, prompting the need for improved detection methods.
- Researchers developed a sensitive and selective sandwich-type immunosensor using electrochemical impedance spectroscopy (EIS) combined with a novel composite material made of gold nanoparticles, reduced-graphene oxide, and graphitic carbon nitride to enhance performance.
- The sensor demonstrated excellent analytical capabilities with a wide detection range and low detection limit for CEA, proving effective and stable for real sample analysis.
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