The considerable health risks associated with fungal infections are continuously rising, thereby requiring proper and efficient antifungal treatment options [...].
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Medication experiences in the treatment of opioid use disorders: Insights from Reddit.
Addiction
March 2025
Division of Infectious Diseases and Global Public Health, University of California San Diego, San Diego, CA, USA.
Background And Aims: Better understanding the challenges faced by patients on medications for opioid use disorder (MOUD), including methadone and buprenorphine, is critical to increasing their use/retention. Social media platforms such as Reddit offer a space for patients to share their experiences with medications. We aimed to identify and characterize challenges faced by patients taking MOUD through analysis of discussions from the r/Methadone and r/suboxone subreddits.
View Article and Find Full Text PDFEthical issues surrounding the implementation of long-acting injectable antiretroviral therapy in sub-Saharan Africa.
Int Health
March 2025
Department of Global Health and Development, London School of Hygiene and Tropical Medicine, P.O Box WC1E 7HT, London, UK.
Background: This article discusses the ethical issues surrounding the integration of long-acting injectable antiretroviral therapy (LA-ART) in the programmatic management of human immunodeficiency virus (HIV). As the medical landscape evolves, implementing LA-ART introduces many ethical issues that should be considered for the success of scale-up in diverse settings.
Methods: This article examines key issues such as bioethical concerns around the rollout of LA-ART, including regulatory requirements, a person's autonomy, informed consent, privacy and confidentiality; the societal implications of providing LA-ART, including the impact on stigma and discrimination; ethics around who receives LA-ART, financial accessibility, equitable access, inclusive decision-making and cultural sensitivity; and the ethics of providing an expensive intervention, including cost-effectiveness, supply chain sustainability and resource allocation.
Digital Platform-Based Conceptual Framework for Food Environment Research in China.
Public Health Nutr
March 2025
Department of Geography, Faculty of Social Science, The University of Hong Kong, Pokfulam, Hong Kong SAR, China.
China has dedicated significant efforts to preventing obesity, but the rising prevalence of overweight and obesity remains a pressing public health issue. Therefore, unique solutions are required to address this challenge in China. As a research priority, the food environment plays a pivotal role in addressing overweight and obesity.
View Article and Find Full Text PDFPGAM5 Modulates Macrophage Polarization, Aggravating Inflammation in COPD via the NF-κB Pathway.
Int J Chron Obstruct Pulmon Dis
March 2025
Department of Respiratory Medicine, The second Affiliated Hospital, Hainan Medical University, Haikou, 570100, People's Republic of China.
Background: Chronic obstructive pulmonary disease (COPD) has emerged as a very consequential issue threatening human life and health; therefore, research on its pathogenesis is urgently needed. A prior investigation discovered a significant elevation in the phosphoglycerate mutase 5 (PGAM5) expression in the lung tissue of COPD smoking patients. This rise in expression is closely associated with COPD severity.
View Article and Find Full Text PDFExamining Predictors of Environmental Health Knowledge and Competences in a Sample of Catalan Paediatricians.
Health Sci Rep
March 2025
Spanish Consortium for Research on Epidemiology and Public Health (CIBERESP), Instituto de Salud Carlos III Madrid Comunidad de Madrid Spain.
Background And Aims: Their close contact with the cokes paediatricians a key group of healthcare professionals for the dissemination of environmental health (EH) notions and the protection of children and families. However, international studies show that their knowledge and competences in EH matters are limited.
Methods: We recruited a sample of 293 paediatricians (80% women, mean age 47 years) working in Catalonia (Spain).
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