Respiratory compliance reflects the ability of the lungs and chest wall to expand in response to increases in pressure. In this review, relevant studies were selected through a comprehensive literature search with the aim of summarizing and generalizing them to describe the relevant factors that may be present in veterinary clinical practice and affect respiratory compliance in dogs. Individual factors, including breeds, disease background, drugs administered, and especially surgical procedures, can result in alterations to respiratory compliance due to their impact on the respiratory system in dogs. Despite its potential clinical utility, such as in anesthesia monitoring, respiratory compliance remains underutilized in veterinary medicine, and further research is necessary to support its future clinical applications.
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http://dx.doi.org/10.3390/ani15050746 | DOI Listing |
Cureus
March 2025
Department of Respiratory Medicine, Nagasaki University Hospital, Nagasaki, JPN.
Background And Objective: For treating community-acquired pneumonia (CAP) in adults, early switching from injectable to oral antimicrobials (switch therapy) is accepted once the clinical course is favorable. Lascufloxacin (LSFX) is a quinolone antibacterial agent, available in intravenous and oral formulations, demonstrating antibacterial activity against a relatively broad spectrum of community-onset pneumonia (COP). No switch therapy using the same drug from injectable to oral antimicrobials has been reported; therefore, we conducted the study to confirm the efficacy and safety of the switch therapy using LSFX.
View Article and Find Full Text PDFIntroduction: Cystic fibrosis (CF) is a severe autosomal recessive disorder caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. This condition disrupts chloride channels and leads to the production of thick, sticky mucus, affecting the respiratory and gastrointestinal systems. CF's prevalence is particularly high in Saudi Arabia, where the incidence has increased from 1 in 2,000 to 1 in 1,000 births.
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February 2025
Pulmonology, Carolina Lung Clinic, Piedmont Medical Center, Rock Hill, USA.
This case report details a 61-year-old male patient with a history of chronic obstructive pulmonary disease (COPD) and significant smoking exposure, who presented with progressive anorexia, weight loss, nocturnal sweating, and worsening respiratory symptoms in early 2024. Imaging revealed bi-apical opacities with cavitation, and sputum cultures identified , a rare nontuberculous mycobacterium (NTM). The patient was managed with a multi-drug regimen including azithromycin, rifampin, and ethambutol, targeting symptom relief, radiographic stability, and sputum conversion.
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February 2025
Cardiovascular Surgery, Kyoto Prefectural University of Medicine, Kyoto, JPN.
Acute respiratory distress syndrome (ARDS) incidence following minimally invasive cardiac surgery (MICS) is rare. We report a case of acute respiratory failure following cardiac surgery that was diagnosed as ARDS. A 77-year-old female patient diagnosed with aortic valve stenosis underwent aortic valve replacement via a right thoracotomy.
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February 2025
Internal Medicine, Henry Ford Health System - Warren, Warren, USA.
Medication-induced pulmonary toxicity is a rare adverse event that may occur with many chemotherapeutic agents, including etoposide. This agent has been found to cause various toxicities, including anaphylaxis, angioedema, hypotension, and pneumonitis. Etoposide is used in chemotherapy regimens for multiple cancers, including germ-cell tumors.
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