The evolution experienced by global society, in the post-COVID 19 era, is marked by the quite obligatory use of digital media in many sectors, as is the case for the health sector. Quite frequently, both patients and health professionals use social media to express their telemedicine concerns or interests. The present research focuses on these social media comments as they represent a very interesting data source for researchers. In the present analysis, we focus on unstructured tweet texts written by Internet users and apply both machine learning and the Latent Dirichlet Allocation algorithm to model X databases and identify tweet topics. The results gathered provide professionals with information on the most important issues and factors of influence for telemedecine consumers.BackgroundThe use of new technologies has transformed society, affecting communication, information seeking and ways of working. Telemedicine, as a remote health practice through ICTs, has grown exponentially, especially after the pandemic.ObjectiveWe do apply a mixed methodology in our study and use both qualitative and quantitative techniques to explore the conversational topics generated about telemedicine through comments posted by users on X. This allows us to identify primary, secondary, and residual themes.MethodsNatural Language Processing (NLP) and Machine Learning techniques, specifically the Latent Dirichlet Allocation (LDA) model, were used to analyse 156,633 comments extracted from "X" related to telemedicine topics.ResultsThe study revealed several issues to be addressed. Data was collected using keywords such as "teleconsultation" and "telemedicine". We can see that the most frequent words in the comments include words such as "health", "service", "doctor" and "patient". The themes identified were grouped into four dimensions: general information, benefits sought, specific information and professional issues. The results showed that 60.1% of the comments focused on generic telemedicine topics, ease of use and service information. "X" queries were observed to be public and general in nature, focusing on benefits and accessibility, while disease or treatment specific topics were less frequent.ConclusionsThe results provide information for the proper development and study of telemedicine through social networks. "X" is a platform mainly used for general telemedicine queries, with convenience and accessibility as the main benefits mentioned. The results suggest that online telemedicine interactions are complex and offer valuable insights for improving telemedicine communication strategies. Future research could explore the use of hashtags and analyse differences in interaction patterns according to user profile, providing a deeper understanding of audiences' behaviour on social networks. These findings underline the importance of considering audience preferences to improve the effectiveness of telemedicine communications.
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Front Med (Lausanne)
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UCL Respiratory, University College London, London, United Kingdom.
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February 2025
Department of Defense Biotechnology High Performance Computing Software Applications Institute, Telemedicine and Advanced Technology Research Center, Defense Health Agency Research and Development, Medical Research and Development Command, Frederick, MD, United States.
Transporters are membrane proteins that are critical for normal cellular function and mediate the transport of endogenous and exogenous chemicals. Chemical interactions with these transporters have the potential to affect the pharmacokinetic properties of drugs. Inhibition of transporters can cause adverse drug-drug interactions and toxicity, whereas if a drug is a substrate of a transporter, it could lead to reduced therapeutic effects.
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February 2025
Anatomy, All India Institute of Medical Sciences, Madurai, Madurai, IND.
This review addresses the significant challenges and technological developments in cancer screening and early diagnosis in the context of India's diverse and resource-constrained healthcare landscape. Selected cancers like breast, cervical, oral, lung, and colorectal cancers are focused on, and established screening methods such as clinical breast examination (CBE), mammography, visual inspection with acetic acid (VIA), HPV DNA testing, and oral visual inspection (OVI) are reviewed. These are cost-effective strategies that are proven to reduce mortality.
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March 2025
College of Food Science and Technology, Yunnan Agricultural University, No. 452 Fengyuan Road, Kunming 650201, China.
A lysosome-targeting chimera (LYTAC) offers a novel strategy for degrading extracellular proteins previously considered to be undruggable by hijacking the lysosomal degradation system. However, clinical use of LYTAC has been limited due to the potential for uncontrolled degradation and systemic toxicity. Based on our previously developed genetically encoded TfR-LYTAC, here, we introduce a photothermal-inducible switch in the engineered bacterium to enable spatiotemporal expression of TfR-LYTAC.
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February 2025
Department of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", University of Salerno, 84081 Baronissi, Italy.
Bariatric surgery (BS) is an effective treatment for severe obesity and its related comorbidities, such as type 2 diabetes and hypertension. However, the anatomical and physiological changes associated with these procedures significantly increase the risk of preoperative and postoperative micronutrient deficiencies, which can lead to severe complications such as anemia, osteoporosis, and neurological disorders. This narrative review examines the prevalence and clinical implications of micronutrient deficiencies in BS patients, as well as evidence-based strategies for their prevention and management.
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