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Pediatr Dent
January 2025
Chief Policy Officer, Research and Policy Center, American Academy of Pediatric Dentistry, Chicago, Ill, and Professor Emeritus, The Ohio State University College of Dentistry, Columbus, Ohio, USA.
The expansion of linear infrastructure presents a significant threat to biodiversity, emphasizing the urgent need for regional studies on spatial variations and comprehensive multispecies research. This study surveyed and monitored wildlife passages across eight nature reserves in Xinjiang, evaluating their construction status, utilization patterns, and key factors influencing utilization rates, as well as providing optimization recommendations. The findings revealed that dedicated wildlife passages were scarce, especially in smaller reserves, which primarily relied on small bridges and culverts originally designed for water flow.
View Article and Find Full Text PDFIdentification and characterization of ternary complexes consisting of FKBP12, MAPRE1 and macrocyclic molecular glues.
RSC Chem Biol
March 2025
Novartis Biomedical Research Fabrikstrasse 2 CH-4056 Basel Switzerland
Many disease-relevant and functionally well-validated targets are difficult to drug. Their poorly defined 3D structure without deep hydrophobic pockets makes the development of ligands with low molecular weight and high affinity almost impossible. For these targets, incorporation into a ternary complex may be a viable alternative to modulate and in most cases inhibit their function.
View Article and Find Full Text PDFDesign Key Points of High-Performance Diffuse Reflectance Optical Sensors for Non-Invasive Blood Glucose Measurement.
Sensors (Basel)
February 2025
State Key Laboratory of Precision Measurement Technology and Instruments, Tianjin University, Tianjin 300072, China.
Optical sensors serve as pivotal components in the realm of non-invasive blood glucose measurement (NBGM) devices, where their efficacy directly influences the detection of weak glucose signals. This research introduces three fundamental design key points tailored for diffuse reflectance optical sensors employed for NBGM: depth resolution, detection signal-to-noise ratio, and human-sensor interface coupling. Guided by these design key points, we presented feasible design proposals for near-infrared diffuse reflectance sensors operating in the range of 1000-1700 nm.
View Article and Find Full Text PDFSustainable nanofiber films based on polylactic acid/modified cellulose nanocrystals containing various types of polyphenols, exhibiting antioxidant activity and high stability.
Food Chem
February 2025
Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences, Key Laboratory of Agro-products Quality and Safety Control in Storage and Transport Process, Ministry of Agriculture and Rural Affairs, Beijing 100193, China; College of Food Science and Engineering, Shanxi Agricultural University, Taigu 030801, China. Electronic address:
The type of phenolic compounds significantly influences the physicochemical properties and biological activities of packaging materials. This study aimed to investigate the effects of caffeic acid (Caf), esculetin (Esc), or quercetin (Que) on the physicochemical and antioxidant properties of polylactic acid/modified cellulose nanocrystals (PM) nanofiber film. FTIR and XRD analyses confirmed the successful encapsulation of Caf, Esc, and Que.
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