Objective: This study aims to evaluate the efficacy and safety of the modified push-through technique in bilateral same-day myringoplasty for patients with chronic otitis media. Bilateral myringoplasty, while advantageous in terms of cost and recovery time, is often avoided due to the perceived risks, particularly iatrogenic sensorineural hearing loss (SNHL). This study contributes to the limited literature on simultaneous bilateral ear surgeries by assessing surgical outcomes, including graft success rates and postoperative hearing improvement.
Methods: A prospective study was conducted on 50 patients (100 ears) undergoing bilateral same-day myringoplasty at a tertiary care center. The modified push-through technique was employed for all surgeries. Postoperative follow-up was carried out at 1, 3, and 6 months, with evaluations including otomicroscopy and audiometric testing. The primary outcome was graft take rate, and secondary outcomes included air-bone gap (ABG) reduction and incidence of SNHL.
Results: The study demonstrated a graft success rate of 94% across the 100 operated ears. Postoperative audiometry revealed significant improvement in hearing, with the ABG reduced from a preoperative mean of 20 dB to a postoperative mean of 10 dB (p < 0.001). No cases of SNHL were observed.
Conclusion: Bilateral same-day myringoplasty using the modified push-through technique is a viable surgical option for patients with chronic otitis media, offering high graft success rates and significant hearing improvement without increasing the risk of SNHL. This technique could be considered a preferred approach in suitable patients, potentially reducing the need for multiple surgical interventions and associated healthcare costs.
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http://dx.doi.org/10.1097/MAO.0000000000004493 | DOI Listing |
Otol Neurotol
March 2025
Otolaryngology Department, Basaksehir Cam ve Sakura City Hospital, University of Health Sciences, Istanbul, Turkey.
Objective: This study aims to evaluate the efficacy and safety of the modified push-through technique in bilateral same-day myringoplasty for patients with chronic otitis media. Bilateral myringoplasty, while advantageous in terms of cost and recovery time, is often avoided due to the perceived risks, particularly iatrogenic sensorineural hearing loss (SNHL). This study contributes to the limited literature on simultaneous bilateral ear surgeries by assessing surgical outcomes, including graft success rates and postoperative hearing improvement.
View Article and Find Full Text PDFMikrochim Acta
August 2024
School of Chemistry and Pharmaceutical Sciences, State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, Guangxi Normal University, Guilin, 541004, China.
An ultrasensitive photothermal assay was designed for point-of-care testing (POCT) of tumor markers based on a filter membrane. Firstly, CuSe was successfully encapsulated in liposome spheres with biotin on the surface and connected to carcinoembryonic antigen (CEA) aptamer with 3'end modified biotin by streptavidin. Secondly, the CEA antibody was successfully modified on the surface of the nitrocellulose membrane through simple incubation.
View Article and Find Full Text PDFArch Acad Emerg Med
January 2022
Men's Health and Reproductive Health Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Removing embedded fishhook without causing further tissue damage from the barbed nature of the hook is a challenge in emergency department (ED). The four most commonly used techniques include advance and cut, string-yank, needle cover, and retrograde removal. This study aims to describe a modified push- through technique without cutting the barb, namely advance without cut and retrograde removal, as an effective technique of successful removal of fishhooks.
View Article and Find Full Text PDFEur Arch Otorhinolaryngol
May 2020
Department of Otorhinolaryngology, Yiwu Central Hospital, 699 Jiangdong Road, Yiwu City, 322000, Zhejiang, China.
Anal Bioanal Chem
November 2009
Center for Analytical Chemistry, Department for Agrobiotechnology (IFA-Tulln), University of Natural Resources and Applied Life Sciences, Vienna (BOKU), Konrad Lorenz Str. 20, 3430 Tulln, Austria.
Cereals and cereal-based food have often been found to be contaminated with the mycotoxins deoxynivalenol (DON) and zearalenone (ZON), after infection of the grain with the pathogenic fungus Fusarium. Both the pathogen and the infected plants can chemically modify DON and ZON, including acetylation, glucosidation, and sulfation. Analytical strategies for detection and quantification of DON and ZON are well known and established but often fail to recognize the respective metabolites, which are, therefore, also referred to as "masked" mycotoxins.
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