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Rescue Spinal Drain After High-Risk Thoracic Endovascular Aortic Repair Is a Patient Safety Issue for Anesthesiologists: The Need for Institutionalized Protocols.
J Cardiothorac Vasc Anesth
February 2025
Ohio State University Wexner Medical Center, Columbus, OH. Electronic address:
Spinal premotor circuits play a fundamental role in motor control. The corticospinal tract (CST) provides control signals to premotor circuits in the spinal cord, guiding voluntary skilled movements. Unilateral selective lesion of the CST in the medullary pyramidal tract (PTX) produces transneuronal degeneration, whereby Choline Acetyltransferase-positive (ChAT) premotor interneurons contralesionally undergo non-apoptotic degeneration by microglial phagocytosis.
View Article and Find Full Text PDFIntrathecal morphine vs. Ultrasound-guided bilateral posterior quadratus lumborum block in caesarean delivery.
J Anesth Analg Crit Care
March 2025
Department of Anesthesiology and Reanimation, School of Medicine, Ondokuz Mayis University, Samsun, Türkiye.
Background: Effective postoperative pain management is crucial in caesarean delivery (CD) to enhance recovery, minimize opioid use, and improve maternal outcomes. Intrathecal morphine (ITM) is widely used but can cause side effects, such as pruritus and nausea. Posterior quadratus lumborum block (QLB) has emerged as a potential alternative for postoperative analgesia.
View Article and Find Full Text PDFIntrathecal magnesium sulphate as an adjuvant to bupivacaine for infraumbilical surgeries: An updated systematic review and meta-analysis.
Indian J Anaesth
January 2025
General Practitioner, Faculty of Medicine, Al Andalus University for Medical Sciences, Tartus, Syria.
Background And Aims: Intrathecal anaesthesia is widely used for infraumbilical surgeries due to its effectiveness in providing pain relief during and after the operation. Adding magnesium sulphate (MgSO) to intrathecal local anaesthetics can prolong analgesia, reduce postoperative analgesic requirements and improve the management of shivering perioperatively. This review aims to investigate the use of intrathecal adjuvant MgSO4 for anaesthesia in infraumbilical surgeries.
View Article and Find Full Text PDFInjectable hydrogel with miR-222-engineered extracellular vesicles ameliorates myocardial ischemic reperfusion injury via mechanotransduction.
Cell Rep Med
February 2025
Cardiac Regeneration and Ageing Lab, Institute of Geriatrics (Shanghai University), Affiliated Nantong Hospital of Shanghai University (The Sixth People's Hospital of Nantong) and School of Life Science, Shanghai University, Nantong 226011, China; Institute of Cardiovascular Sciences, Shanghai Engineering Research Center of Organ Repair, Joint International Research Laboratory of Biomaterials and Biotechnology in Organ Repair (Ministry of Education), School of Life Science, Shanghai University, Shanghai 200444, China. Electronic address:
Cardiac ischemic reperfusion injury (IRI) significantly exacerbates cardiac dysfunction and heart failure, causing high mortality. Despite the severity of IRI, effective therapeutic strategies remain elusive. Acellular cardiac patches have shown considerable efficacy in delivering therapeutics directly to cardiac tissues.
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