The type VI secretion system mediates interbacterial antagonism between Gram-negative bacteria through delivery of toxic effector proteins. A recent comprehensive genomic analysis by Habich et al. reveals interesting features of the evolution of T6SSs and their corresponding effectors in Pseudomonas aeruginosa, raising questions about functional specialization of the system.
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Twists, turns and jumps: T6SS evolution within species.
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Department of Microbiology, University of Washington, Seattle, WA, USA; Howard Hughes Medical Institute, University of Washington, Seattle, WA, USA; Microbial Interactions and Microbiome Center, University of Washington, Seattle, WA, USA. Electronic address:
The type VI secretion system mediates interbacterial antagonism between Gram-negative bacteria through delivery of toxic effector proteins. A recent comprehensive genomic analysis by Habich et al. reveals interesting features of the evolution of T6SSs and their corresponding effectors in Pseudomonas aeruginosa, raising questions about functional specialization of the system.
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The cis-trans isomerization of the C=N bond is generally believed to induce quenching in molecules containing a Schiff base. These molecules typically serve as turn-on sensors for cations, with only a few acting as ratiometric sensors. This study presents a comprehensive investigation into the photophysical processes of an unusual ratiometric sensor for Zn based on Schiff base, utilizing density-functional theory (DFT) and time-dependent DFT (TDDFT).
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