The structure determination and occurrence of curvisetone (), a tricyclic nor-diterpenoid from the tiny Collembola , is reported. Utilizing NMR analysis and mass spectrometry, we identified curvisetone's unique carbon skeleton and its occurrence in various sex and life stages. Curvisetone, carrying an unprecedented carbon tricyclic ring system, is an example of the distinct terpene usage of Collembola, which differentiates them from other arthropods.
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http://dx.doi.org/10.1021/acs.jnatprod.4c01432 | DOI Listing |
J Nat Prod
March 2025
Technische Universität Braunschweig, Institute of Organic Chemistry, Hagenring 30, 38106 Braunschweig, Germany.
The structure determination and occurrence of curvisetone (), a tricyclic nor-diterpenoid from the tiny Collembola , is reported. Utilizing NMR analysis and mass spectrometry, we identified curvisetone's unique carbon skeleton and its occurrence in various sex and life stages. Curvisetone, carrying an unprecedented carbon tricyclic ring system, is an example of the distinct terpene usage of Collembola, which differentiates them from other arthropods.
View Article and Find Full Text PDFInsect Sci
March 2025
School of Life Science, East China Normal University, Shanghai, China.
Insects have evolved a diversity of regulatory mechanisms to determine their sex. Understanding the molecular regulation mechanisms of insect sex determination is of great significance in revealing the general law of insect sex determination and providing potential routes for the genetic manipulation of pest species. Although the sex determination cascade and doublesex (dsx) gene functions have been well described in some holometabolous insects, little is known about this cascade in hemimetabolous insects.
View Article and Find Full Text PDFThe female mosquito's remarkable ability to hunt humans and transmit pathogens relies on her unique biology. Here, we present the Mosquito Cell Atlas (MCA), a comprehensive single-nucleus RNA sequencing dataset of more than 367,000 nuclei from 19 dissected tissues of adult female and male , providing cellular-level resolution of mosquito biology. We identify novel cell types and expand our understanding of sensory neuron organization of chemoreceptors to all sensory tissues.
View Article and Find Full Text PDFAnim Biosci
February 2025
Joint International Research Laboratory of Agriculture and Agri-Product Safety of Ministry of Education of China, Yangzhou University, Yangzhou 225009, China, Yangzhou, China.
Clarifying the intricate mechanisms underlying sex determination and differentiation regulation in chickens holds significant potential for advancing chicken sex control technologies. This endeavor not only augments fundamental research in developmental biology but also bolsters the economic viability of the poultry industry. Our investigation delved into the sex determination and differen-tiation molecular underpinnings of these processes during the early stages of chicken embryonic development E0 d blastocysts, E3.
View Article and Find Full Text PDFGenome Res
March 2025
Max Planck Institute for Biology Tübingen, Department of Molecular Biology, 72076 Tübingen, Germany;
The guppy Y Chromosome has been a paradigmatic model for studying the genetics of sex-linked traits and Y Chromosome-driven evolution for more than a century. Despite strong efforts, knowledge on genomic organization and molecular differentiation of the sex chromosome pair remains unsatisfactory and partly contradictory with respect to regions of reduced recombination. Especially the border between pseudoautosomal and male-specific regions of the Y has not been defined so far.
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