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Bringing MedEd Interventions From the Bench to the Bedside: Applying Implementation Science to Pulmonary and Critical Care Medical Education.
Chest
March 2025
Division of Pulmonary/Critical Care Medicine and Medical Informatics and Clinical Epidemiology, Oregon Health & Science University, Portland, OR; Division of Pulmonary/Critical Care Medicine, University of California, San Francisco, San Francisco, CA.
Classification of non-TCGA cancer samples to TCGA molecular subtypes using compact feature sets.
Cancer Cell
February 2025
Department of Epigenetics, Van Andel Institute, Grand Rapids, MI 49503, USA. Electronic address:
Molecular subtypes, such as defined by The Cancer Genome Atlas (TCGA), delineate a cancer's underlying biology, bringing hope to inform a patient's prognosis and treatment plan. However, most approaches used in the discovery of subtypes are not suitable for assigning subtype labels to new cancer specimens from other studies or clinical trials. Here, we address this barrier by applying five different machine learning approaches to multi-omic data from 8,791 TCGA tumor samples comprising 106 subtypes from 26 different cancer cohorts to build models based upon small numbers of features that can classify new samples into previously defined TCGA molecular subtypes-a step toward molecular subtype application in the clinic.
View Article and Find Full Text PDFCharge carrier mobility and electronic properties of Al(Op)3: impact of excimer formation.
Beilstein J Nanotechnol
July 2015
Institute of Nanotechnology, Karlsruhe Institute of Technology, D-76344 Eggenstein-Leopoldshafen, Germany.
We have studied the electronic properties and the charge carrier mobility of the organic semiconductor tris(1-oxo-1H-phenalen-9-olate)aluminium(III) (Al(Op)3) both experimentally and theoretically. We experimentally estimated the HOMO and LUMO energy levels to be -5.93 and -3.
View Article and Find Full Text PDFEffect of seed treatment with organic acids on the control of common bunt (Tilletia tritici and T. laevis) in wheat.
Meded Rijksuniv Gent Fak Landbouwkd Toegep Biol Wet
March 2003
Department of Plant Protection, Damascus University, Syria.
Common bunt caused by Tilletia tritici and T. laevis is an important disease, causes considerable losses in wheat yield on a world wild. The disease reduces yields, complicates harvesting and lowers the quality of the grain.
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