Advancements, functionalization techniques, and multifunctional applications in biomedical and industrial fields of electrospun pectin nanofibers: A review.

Electrospun pectin nanofibers have emerged as a transformative advancement in biomaterials, offering remarkable potential across diverse biomedical and industrial applications. This review explores the synthesis, optimization, and versatile applications of electrospun pectin nanofibers, highlighting their unique properties, including biocompatibility, biodegradability, and adaptability for functionalization. Pectin's structural diversity, coupled with its ability to form hydrogels and interact with biological systems, makes it a promising candidate for wound healing, drug delivery, tissue engineering, and smart packaging. Electrospinning has enabled the fabrication of pectin nanofibers with tunable morphology and functionality, overcoming traditional limitations such as poor mechanical strength. Advances in blending pectin with other polymers and incorporating bioactive agents have further enhanced their mechanical, biological, and therapeutic properties. In wound healing, pectin nanofibers mimic the extracellular matrix, promote angiogenesis, and deliver bioactive compounds to accelerate tissue regeneration. Challenges such as scalability, regulatory compliance, and mechanical limitations remain barriers to widespread adoption. This review underscores the need for interdisciplinary research to address these challenges and advance the clinical and commercial translation of pectin nanofibers. By critically analyzing recent advancements and outlining future directions, this review highlights the transformative potential of electrospun pectin nanofibers as sustainable, high-performance biomaterials for modern biomedical and industrial applications.