The American Academy of Ophthalmology has published several guidelines on dosing and screening recommendations for hydroxychloroquine. In this cross-sectional study we report 36% of patients prescribed hydroxychloroquine at the University of California are excessively dosed.
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iBCS: 4. Application of the Inhalation Biopharmaceutics Classification System to the Development of Orally Inhaled Drug Products.
Mol Pharm
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Merck & Co., Inc., Rahway, New Jersey 07065, United States.
This is the fourth paper in a series describing an inhalation biopharmaceutics classification system (iBCS), an initiative supported by the Product Quality Research Institute. The paper examines the application of the inhalation Biopharmaceutics Classification System (iBCS) through the drug discovery, development, and postapproval phases for orally inhaled drug products (OIDP) and for the development of generic OIDPs. We consider the implication of the iBCS class in terms of product performance and identify the practical gaps that must be filled to enable the classification system to be adopted into day-to-day practice.
View Article and Find Full Text PDFThe Shadow Pandemic Contextualised: Albania's Response to Domestic Violence During COVID-19.
Int J Health Plann Manage
March 2025
Vice Provost for Faculty Affairs, University of Denver, Denver, Colorado, USA.
Background: Domestic violence (DV) encompasses a pattern of psychological, physical, sexual, financial, and/or emotional abuse, manifesting through assault, threats, and intimidation. Economic and social stressors in conjunction with the COVID-19 pandemic escalated DV cases worldwide, including those in Albania. Socioeconomic vulnerabilities worsened the situation, with DV-related complaints to non-governmental organizations (NGOs) in Albania increasing by 60% between March and May 2020, compared to the same period in 2019.
View Article and Find Full Text PDFPrevalence of Metabolic Syndrome and Combinations of Its Components: Findings from the Mexican National Health and Nutrition Survey, 2021.
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Center for Nutrition and Health Research, National Institute of Public Health, Cuernavaca, México.
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Addiction
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Division of Infectious Diseases and Global Public Health, University of California San Diego, San Diego, CA, USA.
Background And Aims: Better understanding the challenges faced by patients on medications for opioid use disorder (MOUD), including methadone and buprenorphine, is critical to increasing their use/retention. Social media platforms such as Reddit offer a space for patients to share their experiences with medications. We aimed to identify and characterize challenges faced by patients taking MOUD through analysis of discussions from the r/Methadone and r/suboxone subreddits.
View Article and Find Full Text PDFEthical issues surrounding the implementation of long-acting injectable antiretroviral therapy in sub-Saharan Africa.
Int Health
March 2025
Department of Global Health and Development, London School of Hygiene and Tropical Medicine, P.O Box WC1E 7HT, London, UK.
Background: This article discusses the ethical issues surrounding the integration of long-acting injectable antiretroviral therapy (LA-ART) in the programmatic management of human immunodeficiency virus (HIV). As the medical landscape evolves, implementing LA-ART introduces many ethical issues that should be considered for the success of scale-up in diverse settings.
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