The aim of this study was to evaluate the temperature changes of sodium hypochlorite (NaOCl) after the use of different activation techniques: passive ultrasonic irrigation (PUI), XP-Endo Finisher (XP), and Easy Clean (EC).Thirty patients were selected for this randomized crossover study and each patient received root canal treatment in maxillary incisor. Each tooth was subjected to three activation techniques in a random order in the final irrigation of the treatment. All irrigation was performed using a 2.5% NaOCl solution, with the solution's temperature stabilized at 21°C (baseline) in the syringe. No agitation was used as a control before the use of the devices. After each activation technique, the intracanal temperature was measured using a K-type thermocouple. Statistical analyses were performed using Kruskal-Wallis and Dunn tests.Temperatures remain in the range of 21.0 to 21.2°C at baseline and were higher in the control (29.5-34.1°C), PUI (29.9-34.2°C), EC (29.8-35.6°C), and XP (29.9-34.7°C) groups. The temperature average of the baseline period was inferior to those observed in all groups; moreover, despite of temperature changes among the control and all experimental groups no difference between them were identified.The temperature increase caused by activation with PUI, EC, and XP was similar and did not exceed the levels observed when no agitation was performed.
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http://dx.doi.org/10.1055/s-0044-1791685 | DOI Listing |
J Am Chem Soc
March 2025
Institute of Biological Chemistry, Academia Sinica, No. 128, Sec. 2, Academia Road, Nankang, Taipei 115, Taiwan.
In this study, the role of phosphorylation in the liquid-liquid phase separation (LLPS) of tau, the underlying driving forces, and the potential implications of this separation on protein conformation and subsequent protein aggregation were investigated. We compared in vivo-produced phosphorylated tau (p-tau) and nonphosphorylated tau under different coacervation conditions without adding crowding agents. Our findings revealed that spontaneous phase separation occurs exclusively in p-tau, triggered by a temperature shift from 4 °C to room temperature, and is driven by electrostatic and hydrophobic interactions.
View Article and Find Full Text PDFJ Allergy Clin Immunol Pract
March 2025
Department of Pediatrics, College of Medicine, Hanyang University, Seoul, Korea. Electronic address:
Climate change will continue to impact allergic diseases in direct and indirect ways. Rising global temperatures are contributing to increased duration of pollen seasons, altered aeroallergen production and potency of allergens, and changes in the geographic distribution of allergenic plants that drive increased human exposure to aeroallergens and increased allergic disease morbidity. Climate change is inextricably linked with air pollution, the latter of which was shown to act as an adjuvant for allergic inflammatory processes promoting allergic sensitization.
View Article and Find Full Text PDFEur J Dent
March 2025
Conservative surgery Department, Collage of Oral and Dental Surgery, Misr University for Science and Technology (MUST), Giza, Egypt.
The aim of this study was to evaluate the temperature changes of sodium hypochlorite (NaOCl) after the use of different activation techniques: passive ultrasonic irrigation (PUI), XP-Endo Finisher (XP), and Easy Clean (EC).Thirty patients were selected for this randomized crossover study and each patient received root canal treatment in maxillary incisor. Each tooth was subjected to three activation techniques in a random order in the final irrigation of the treatment.
View Article and Find Full Text PDFEnviron Pollut
March 2025
College of Animal Science and Technology, Inner Mongolia Minzu University, Tongliao, Inner Mongolia, 028000, China; Inner Mongolia Key Laboratory of Toxicant Monitoring and Toxicology. Electronic address:
Global warming causes the release of dioxin-like deposits and increases geographical migration, increasing the risk of exposure for humans and animals. In this experiment, we used CYP1A transgenic zebrafish Tg (cyp1a: mCherry) and liver fluorescent transgenic zebrafish Tg (fabp10: Ps Red) as an animal model and exposed to 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD) at 26 °C and 30 °C, respectively. Morphological changes, histological changes, transcriptome and related genes expression were detected.
View Article and Find Full Text PDFSci Total Environ
March 2025
SINTEF Ocean AS, Dept. Climate and Environment, Trondheim, Norway.
Seasonal dynamics can vastly influence the natural depletion of oil spilled into the ocean and the Arctic regions are characterized by large seasonal changes, especially in temperature and daylight. To determine the influences of seasonal variation on natural oil depletion processes like dissolution, photooxidation and biodegradation, we deployed thin films of three oils in natural seawater during the Arctic summer and winter in Svalbard, Norway. The extent of oil depletion varied with season and the type of the oil, however, considerable depletion of n-alkanes and polycyclic aromatic compounds were observed during both summer and winter.
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