As cancer becomes more of a chronic condition, cancer rehabilitation care aimed at maintaining and improving patients' quality of life(QOL)is becoming increasingly important. Cancer rehabilitation care addresses both disabilities caused by cancer itself and those that arise during the treatment process. Cancer rehabilitation is divided into four phases-preventive, restorative, supportive, and palliative. During the perioperative period, prehabilitation starting before surgery aims to prevent complications and promote recovery, while during chemotherapy and radiation therapy, the focus is on preventing inactivity and maintaining/improving physical and social functioning. For patients with advanced cancer, addressing cancer cachexia and bone metastases is crucial. Cachexia is managed through a multidisciplinary approach combining exercise therapy and nutritional management, while for bone metastases, early detection and appropriate use of orthoses help prevent pathological fractures. In the terminal phase, support focuses on maintaining QOL while prioritizing the wishes of patients and their families. Since the enactment of the"Cancer Control Act"in 2006, the infrastructure for cancer rehabilitation has been developing, and in 2010, "Cancer Patient Rehabilitation Fee"was newly established in the medical fee schedule. In terms of human resource development, professional training is being conducted through cancer rehabilitation training programs and cancer professional development plans. Going forward, there is a need for stage-specific treatment approaches, individualized care according to life stages, and strengthened multi-professional collaboration in advanced cancer care. With the increase in elderly cancer patients, cancer becoming a chronic condition, and more patients living with cancer, maintaining functional capacity and extending healthy life expectancy have become more important goals than just extending survival time. The provision of comprehensive, evidence-based rehabilitation care has become essential.
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Int J Biol Macromol
March 2025
Department of Rheumatism and Immunology, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei 050000, China.
Chronic pain is a significant public health concern that diminishes patients' quality of life and imposes considerable socioeconomic costs. Effective pharmacological treatments for ongoing pain are limited. Recent studies have indicated that various models of chronic pain-such as neuropathic pain, inflammatory pain, and pain associated with cancer-have abnormal levels of long noncoding RNAs (lncRNAs).
View Article and Find Full Text PDFCancer Lett
March 2025
Department of Dermatology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China; Frontier Institute of Science and Technology, Xi'an Jiaotong University, Xi'an, China; School of Health and Life Sciences, University of Health and Rehabilitation Sciences, Qingdao, China; Interdisciplinary Research Center of Frontier science and technology, Xi'an Jiaotong University, Xi'an, China. Electronic address:
Mitochondrial malfunction is traditionally viewed as a major factor in tumor growth and malignancy, while recent studies have introduced conflicting views suggesting the necessity of functional mitochondria for tumor growth. Despite these differing perspectives, the specific role of mitochondria in cutaneous squamous cell carcinoma (cSCC) remains poorly understood. In this study, we observed increased mitochondrial abundance and function during the development of cSCC.
View Article and Find Full Text PDFGan To Kagaku Ryoho
February 2025
Dept. of Digestive Surgery, Kyoto First Red Cross Hospital.
Robotic gastrectomy is a safe and minimally invasive approach that may reduce the risk of complications in patients with severely impaired pulmonary function. Here, we report the successful treatment of an 80-year-old patient with gastric cancer and myasthenia gravis(MG)using perioperative respiratory rehabilitation and robotic gastrectomy with D2 lymphadenectomy. Patients with gastric cancer and severe pulmonary dysfunction are at a risk of postoperative respiratory disorders, including severe pneumonia.
View Article and Find Full Text PDFGan To Kagaku Ryoho
February 2025
Dept. of Medical Oncology, Kyorin University Faculty of Medicine.
Aging is a risk factor for cancer, and the number of older adults with cancer is rising. When delivering cancer care for this population, it is essential to assess not only the cancer but also the individual as an older adult. Accurate evaluation requires understanding the biological, physiological, and social characteristics associated with aging.
View Article and Find Full Text PDFGan To Kagaku Ryoho
February 2025
Dept. of Rehabilitation Medicine, Keio University School of Medicine.
As cancer becomes more of a chronic condition, cancer rehabilitation care aimed at maintaining and improving patients' quality of life(QOL)is becoming increasingly important. Cancer rehabilitation care addresses both disabilities caused by cancer itself and those that arise during the treatment process. Cancer rehabilitation is divided into four phases-preventive, restorative, supportive, and palliative.
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