Context: In 2023, we employed Dexcom G6 for real-time continuous glucose monitoring (rt-CGM); it showed high usefulness but unsatisfactory accuracy in type 1 diabetes summer camp (camp) participants.
Objective: To assess the usefulness, recommendation and accuracy of a new rt-CGM system in camp, 2024.
Methods: Sensor glucose (SG) concentrations were measured by Dexcom G7 (G7) from 6 days prior to camp. Usefulness and recommendation were assessed by questionnaire. Twenty-one children with type 1 diabetes and 52 healthcare providers (HCPs) participated. CGM-associated metrics were measured 6 days prior to (off camp: 6 days) and during camp (on camp: 2 days).
Results: G7 was rated highly for its sensor insertion, visualization of SG variation and convenience during camp. The SG value accuracy scored relatively low. G7's usefulness and recommendation among campers were significantly higher than those of G6, utilized the previous year, and they were both almost equally highly rated by HCPs. The mean absolute relative difference (MARD) was 11.3% (G6: 16.0%) on camp and 11.0% (G6: 19.7%) off camp. The coefficient of variation was 34.4% (G6: 60.3%) on camp and 35.9% (G6: 63.1%) off camp, while the glucose management indicator was 7.44% for G7 (G6: 8.04%). The glycemic management metrics on camp were better than those off camp. Graphical analyses also showed sufficient accuracy.
Conclusion: G7 was rated higher in usefulness and recommendation than G6 among participants. G7 also exhibited improved accuracy and was considered a useful rt-CGM tool in a camp setting. Glucose management on camp was significantly improved because of the HCPs' multi-directional efforts.
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http://dx.doi.org/10.1210/clinem/dgaf160 | DOI Listing |
J Clin Endocrinol Metab
March 2025
Department of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University. 1-1-1 Honjo, Chuo-ku, Kumamoto 860-8556, Japan.
Context: In 2023, we employed Dexcom G6 for real-time continuous glucose monitoring (rt-CGM); it showed high usefulness but unsatisfactory accuracy in type 1 diabetes summer camp (camp) participants.
Objective: To assess the usefulness, recommendation and accuracy of a new rt-CGM system in camp, 2024.
Methods: Sensor glucose (SG) concentrations were measured by Dexcom G7 (G7) from 6 days prior to camp.
Omega (Westport)
March 2025
Centre for Mental Health and Community Wellbeing, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC, Australia.
Experiencing the death of a loved one is a stressful and disruptive event that can have short-term and long-term detrimental effects on the grief, mental health, and social functioning of the bereaved individuals. Grief camps represent a relatively novel form of support. However, little is known about their effectiveness.
View Article and Find Full Text PDFReprod Sci
March 2025
Departments of Obstetrics and Gynecology and Biochemistry and Molecular Biology, the C.S. Mott Center for Human Growth and Development, Wayne State University School of Medicine, Detroit, MI, 48201, USA.
Glyphosate-based herbicides (GBHs) are the most widely used herbicides in the United States, accounting for 19% of estimated global use. Although the Environmental Protection Agency (EPA) has reaffirmed that the active ingredient glyphosate (GLY) is safe for humans, recent studies on exposure have suggested association with cancer, metabolic disorders, endocrine disruption and infertility, Alzheimer's and Parkinson's disease, and psychological disorders. Current literature on the effects of GLY exposure on reproductive function suggests potential clinical implications on women's reproductive health, including polycystic ovarian syndrome (PCOS), endometriosis, infertility, and adverse pregnancy outcomes.
View Article and Find Full Text PDFInt J Comput Assist Radiol Surg
March 2025
CAMP, Technical University of Munich, Munich, Germany.
Purpose: The multi-modality imaging system offers optimal fused images for safe and precise interventions in modern clinical practices, such as computed tomography-ultrasound (CT-US) guidance for needle insertion. However, the limited dexterity and mobility of current imaging devices hinder their integration into standardized workflows and the advancement toward fully autonomous intervention systems. In this paper, we present a novel clinical setup where robotic cone beam computed tomography (CBCT) and robotic US are pre-calibrated and dynamically co-registered, enabling new clinical applications.
View Article and Find Full Text PDFStem Cells
March 2025
Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Faculty of Health and Medical Sciences, University of Copenhagen, 2200, Copenhagen, Denmark.
Cell replacement therapies using human pluripotent stem cell-derived ventral midbrain (VM) dopaminergic (DA) progenitors are currently in clinical trials for treatment of Parkinson's disease (PD). Recapitulating developmental patterning cues, such as fibroblast growth factor 8 (FGF8), secreted at the midbrain-hindbrain boundary (MHB), is critical for the in vitro production of authentic VM DA progenitors. Here, we explored the application of alternative MHB-secreted FGF-family members, FGF17 and FGF18, for VM DA progenitor patterning.
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