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Tigecycline for the Treatments of Severe Clostridioides difficile Infection in Pediatric Immunocompromised Patients.
Pediatr Infect Dis J
March 2025
Infectious Diseases Unit, Department of Pediatrics, IRCCS Istituto Giannina Gaslini, Genoa, Italy.
Increasing polymyxin resistance in clinical carbapenem-resistant Klebsiella pneumoniae strains in China between 2000 and 2023.
Commun Med (Lond)
March 2025
Department of Clinical Laboratory, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China.
Background: Development of polymyxin resistance in carbapenem-resistant Klebsiella pneumoniae (CRKP) poses a severe challenge to public health. Here we aimed to perform a retrospective study of prevalence and molecular characteristics of polymyxin-resistant CRKP strains.
Methods: 4455 clinical CRKP strains from 18 provinces in China during 2000 to 2023 were collected.
Carbapenem-resistant infections after liver transplantation: Drug resistance, risk factors and impact on prognosis.
World J Gastroenterol
February 2025
Department of Transplant Surgery, The Third Xiangya Hospital of Central South University, Changsha 410013, Hunan Province, China.
Background: Liver transplant (LT) recipients are susceptible to carbapenem-resistant (CRKP) infections. Comprehensive research addressing the incidence, timing, infection sites, resistance patterns, treatment options, and associated risk factors among LT recipients with CRKP is now lacking.
Aim: To assess the incidence, resistance, therapy, and risk factors of CRKP infections post-LT, and to evaluate the impact of them on prognosis.
Microbial Pathogen Spectrum in Anastomotic Leaks after Ivor-Lewis Esophagectomy.
Surg Infect (Larchmt)
March 2025
Department of Anesthesiology and Intensive Care Medicine, Kliniken Maria Hilf, Mönchengladbach, Germany.
Anastomotic leaks after esophagectomy cause significant morbidity and mortality. In addition to their early detection and prompt endoscopic or surgical management, providing adequate antimicrobial agents is a fundamental aspect of therapy. In this study, different types of microbiological samples were analyzed to provide insight into the microbial pathogen spectrum of anastomotic leaks after esophagectomy.
View Article and Find Full Text PDFCase Report: Management of recurrent UTI with tigecycline in a kidney transplant recipient.
Front Transplant
February 2025
JSS Medical College and Hospital, JSS Academy of Higher Education and Research, Mysuru, India.
This case report describes a 37-year-old man who underwent renal transplantation and subsequently developed complicated recurrent urinary tract infections (UTIs) caused by multidrug-resistant (MDR) . Despite initial treatment with fosfomycin and meropenem, the patient experienced persistent UTIs, leading to multiple hospitalizations. The management of these recurrent infections eventually required the use of tigecycline.
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