Febrile infants 8-60 days of age underwent multiplex polymerase chain reaction (mPCR) testing in the emergency department. The virus-positive rate was 61.3%, with serious bacterial infections (SBIs) at 12.5%, invasive bacterial infections (IBIs) at 3.6%, and urinary tract infections (UTIs) at 8.9%. mPCR-positive cases demonstrated lower frequencies of SBIs, IBIs and UTIs; however, the number of IBIs was limited.
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http://dx.doi.org/10.1097/INF.0000000000004789 | DOI Listing |
Pediatr Infect Dis J
March 2025
Department of Pediatrics and Intensive Care Medicine.
Background: To evaluate the disease burden, risk of complications and mortality in children with viral detection during the peri-liver transplant period.
Methods: A retrospective cohort study was conducted between January 2020 and December 2023 at a tertiary university hospital. Children who underwent multiplex polymerase chain reaction testing from 7 days before to 14 days after liver transplantation were included.
Pediatr Infect Dis J
March 2025
From the Department of Emergency and Transport Medicine, National Center for Child Health and Development, Tokyo, Japan.
Febrile infants 8-60 days of age underwent multiplex polymerase chain reaction (mPCR) testing in the emergency department. The virus-positive rate was 61.3%, with serious bacterial infections (SBIs) at 12.
View Article and Find Full Text PDFPLoS One
March 2025
Instituto de Investigación en Zoonosis (CIZ), Universidad Central del Ecuador, Quito, Ecuador.
Anaplasmosis is a tick-borne disease (TBDs) caused by Anaplasma spp. In areas where TBDs are endemic, it is crucial to consider the animals' immunological status in relation to these diseases. The true prevalence of bovine anaplasmosis, the percentage of animals with protective antibodies against this TBD, and the diagnostic characteristics of three tests (multiplex polymerase chain reaction (mPCR), competitive-inhibition enzyme-linked immunosorbent assay (cELISA), and blood smear (BS)) were estimated using a Bayesian approach.
View Article and Find Full Text PDFBalkan J Med Genet
December 2024
Research Center for Genetic Engineering and Biotechnology "Georgi D. Efremov", Macedonian Academy of Sciences and Arts, Skopje, North Macedonia, Skopje, North Macedonia.
Pregnancy loss (PL), particularly early pregnancy loss (EPL), is a prevalent reproductive complication, with approximately 15% of confirmed pregnancies affected. Chromosomal abnormalities are implicated in more than half of EPLs, with trisomies being the most prevalent. Partial abnormalities, including segmental deletions, duplications, and unbalanced translocations, are detected in up to 10% of EPL cases.
View Article and Find Full Text PDFOpen Forum Infect Dis
December 2024
Institute for Infection and Immunity, St George's, University of London, London, UK.
Background: Epidemiological evidence about the etiology and antimicrobial resistance of neonatal infections remains limited in low-resource settings. We aimed to describe the etiology of neonatal infections in a prospective observational cohort study conducted at two hospital sites in Kampala, Uganda.
Methods: Babies admitted to either unit with risk factors or signs of sepsis, pneumonia, or meningitis had a blood culture, nasopharyngeal swab, and lumbar puncture (if indicated) collected.
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