Background: The increasing integration of artificial intelligence (AI) systems into critical societal sectors has created an urgent demand for robust privacy-preserving methods. Traditional approaches such as differential privacy and homomorphic encryption often struggle to maintain an effective balance between protecting sensitive information and preserving data utility for AI applications. This challenge has become particularly acute as organizations must comply with evolving AI governance frameworks while maintaining the effectiveness of their AI systems.
Objective: This paper aims to introduce and validate data obfuscation through latent space projection (LSP), a novel privacy-preserving technique designed to enhance AI governance and ensure responsible AI compliance. The primary goal is to develop a method that can effectively protect sensitive data while maintaining essential features necessary for AI model training and inference, thereby addressing the limitations of existing privacy-preserving approaches.
Methods: We developed LSP using a combination of advanced machine learning techniques, specifically leveraging autoencoder architectures and adversarial training. The method projects sensitive data into a lower-dimensional latent space, where it separates sensitive from nonsensitive information. This separation enables precise control over privacy-utility trade-offs. We validated LSP through comprehensive experiments on benchmark datasets and implemented 2 real-world case studies: a health care application focusing on cancer diagnosis and a financial services application analyzing fraud detection.
Results: LSP demonstrated superior performance across multiple evaluation metrics. In image classification tasks, the method achieved 98.7% accuracy while maintaining strong privacy protection, providing 97.3% effectiveness against sensitive attribute inference attacks. This performance significantly exceeded that of traditional anonymization and privacy-preserving methods. The real-world case studies further validated LSP's effectiveness, showing robust performance in both health care and financial applications. Additionally, LSP demonstrated strong alignment with global AI governance frameworks, including the General Data Protection Regulation, the California Consumer Privacy Act, and the Health Insurance Portability and Accountability Act.
Conclusions: LSP represents a significant advancement in privacy-preserving AI, offering a promising approach to developing AI systems that respect individual privacy while delivering valuable insights. By embedding privacy protection directly within the machine learning pipeline, LSP contributes to key principles of fairness, transparency, and accountability. Future research directions include developing theoretical privacy guarantees, exploring integration with federated learning systems, and enhancing latent space interpretability. These developments position LSP as a crucial tool for advancing ethical AI practices and ensuring responsible technology deployment in privacy-sensitive domains.
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http://dx.doi.org/10.2196/70100 | DOI Listing |
JMIRx Med
March 2025
Stelmith, LLC, 2333 Aberdeen Pl, Carollton, TX, 75007, United States, 1 9459001314.
Background: The increasing integration of artificial intelligence (AI) systems into critical societal sectors has created an urgent demand for robust privacy-preserving methods. Traditional approaches such as differential privacy and homomorphic encryption often struggle to maintain an effective balance between protecting sensitive information and preserving data utility for AI applications. This challenge has become particularly acute as organizations must comply with evolving AI governance frameworks while maintaining the effectiveness of their AI systems.
View Article and Find Full Text PDFIEEE J Biomed Health Inform
March 2025
Steady state visually evoked potential (SSVEP)-based brain-computer interfaces (BCIs), which are widely used in rehabilitation and disability assistance, can benefit from real-time emotion recognition to enhance human-machine interaction. However, the learned discriminative latent representations in SSVEP-BCIs may generalize in an unintended direction, which can lead to reduced accuracy in detecting emotional states. In this paper, we introduce a Valence-Arousal Disentangled Representation Learning (VADL) method, drawing inspiration from the classical two-dimensional emotional model, to enhance the performance and generalization of emotion recognition within SSVEP-BCIs.
View Article and Find Full Text PDFPurpose: To investigate the association between cognition, social engagement, physical well-being, and emotional well-being in a diverse older population.
Method: A secondary data analysis was conducted using a factor score structural equation model in a multiethnic sample of African American, Afro-Caribbean, Hispanic American, and European American participants.
Results: Statistically significant (direct effects) between the latent constructs of physical well-being, emotional well-being, and social engagement were found.
Med Biol Eng Comput
March 2025
School of Electrical and Information Engineering, Beijing University of Civil Engineering and Architecture, No.15, Yongyuan Road, Huangcun Town, Daxing District, Beijing, 102616, China.
Convolutional neural networks (CNNs) have achieved remarkable success in computer vision, particularly in medical image segmentation. U-Net, a prominent architecture, marked a major breakthrough and remains widely used in practice. However, its uniform downsampling strategy and simple stacking of convolutional layers in the encoder limit its ability to capture rich features at multiple depths, reducing its efficiency for rapid image processing.
View Article and Find Full Text PDFClustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-associated proteins (Cas) systems have revolutionized genome editing by providing high precision and versatility. However, most genome editing applications rely on a limited number of well-characterized Cas9 and Cas12 variants, constraining the potential for broader genome engineering applications. In this study, we extensively explored Cas9 and Cas12 proteins and developed CasGen, a novel transformer-based deep generative model with margin-based latent space regularization to enhance the quality of newly generative Cas9 and Cas12 proteins.
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