There are many studies, both abroad and in Turkey, on the detection of antibiotic residues in animal products. However, studies on this subject in the Hatay region are rare. Within the scope of this study, the presence of 14 types of antibiotic residues (ampicillin, amoxycillin, demeclocycline, doxycycline, enrofloxacin, chlortetracycline, novobiocin, oxytetracycline, penicillin G, streptomycin, sulphadimethoxine, sulphamethazine, tetracycline, and tylosin) in samples from animal products such as beef, poultry, milk, and eggs sold unbranded in Hatay were investigated using HPLC. Total antibiotic residues were between 0.257 and 0.891 mg kg in poultry, between 0.357 and 0.971 mg kg in mutton, between 0.077 and 0.218 mg kg in beef, between 0.591 and 1.985 mg L in milk, and between 0.006 and 1.605 mg kg in egg samples. Antibiotic residues were detected in all samples examined. This shows that some manufacturers are still careless regarding the correct application of antibiotics.
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http://dx.doi.org/10.1080/19393210.2025.2478628 | DOI Listing |
Food Addit Contam Part B Surveill
March 2025
Faculty of Veterinary Medicine, Department of Animal Nutrition and Nutritional Diseases, Hatay Mustafa Kemal University, Hatay, Turkey.
There are many studies, both abroad and in Turkey, on the detection of antibiotic residues in animal products. However, studies on this subject in the Hatay region are rare. Within the scope of this study, the presence of 14 types of antibiotic residues (ampicillin, amoxycillin, demeclocycline, doxycycline, enrofloxacin, chlortetracycline, novobiocin, oxytetracycline, penicillin G, streptomycin, sulphadimethoxine, sulphamethazine, tetracycline, and tylosin) in samples from animal products such as beef, poultry, milk, and eggs sold unbranded in Hatay were investigated using HPLC.
View Article and Find Full Text PDFNucleic Acids Res
February 2025
Protein-Nucleic Acid Interaction Section, Center for Structural Biology, Center for Cancer Research, National Cancer Institute, Frederick, MD, 21702, United States.
Synthetic RNA devices are engineered to control gene expression and offer great potential in both biotechnology and clinical applications. Here, we present multidisciplinary structural and biochemical data for a tetracycline (Tc)-responsive RNA device (D43) in both ligand-free and bound states, providing a structure-dynamical basis for signal transmission. Activation of self-cleavage is achieved via ligand-induced conformational and dynamical changes that stabilize the elongated bridging helix harboring the communication module, which drives proper coordination of the catalytic residues.
View Article and Find Full Text PDFProbiotics Antimicrob Proteins
March 2025
Instituto de Ciencias Básicas, Universidad Veracruzana, Avda. Castelazo Anaya S/N. Cp 91190. Industrial Ánimas, Xalapa, Veracruz, Mexico.
As antibiotic-resistant bacteria emerge, antimicrobial peptides have become a promising alternative due to their safety, low residue, and low resistance properties. This study evaluated the in vitro antibacterial activity of peptides obtained from the fermentation of a halotolerant Lactiplantibacillus plantarum CH. Moreover, an in silico antimicrobial activity of L.
View Article and Find Full Text PDFFood Chem
March 2025
Institute of Resources & Environment, Henan Polytechnic University, Jiaozuo, Henan 454000, China. Electronic address:
Developing analytical methods for simultaneous detection of multiple antibiotic residues is crucial for environmental protection and human health. In this study, a dual lanthanide fluorescence probe (GDP-Eu-Tb) based on nucleotides has been designed. The addition of quinolone antibiotics (QNs) quench the Eu fluorescence signal through the inner filter effect (IFE) and exhibit characteristic peaks, enabling ratio fluorescence detection of levofloxacin (LVLX), gatifloxacin (GTLX), and moxifloxacin (MXLX).
View Article and Find Full Text PDFJ Biochem Mol Toxicol
March 2025
Department of Pharmacy, University of Salerno, Fisciano, Salerno, Italy.
Gap Junctions channels formed by Connexins (Cx) provide intercellular communication enabling the coordination of cell growth, differentiation, and metabolism, and their reduction has been shown in many tumor types. Expression levels of Cx43, the most extensively studied Gap Junctions forming protein, are reduced or completely absent in breast cancer cells, while their overexpression correlates with increased cellular permeability to anticancer agents and, consequently, reduced resistance to drug treatments. So, drug associations targeting Cx43 are being considered to overcome chemoresistance.
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