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Overcoming three-dimensional challenges through objective decomposition and virtual-digital design: A multidisciplinary case on hypodontia treatment.
J World Fed Orthod
March 2025
Assistant professor, State Key Laboratory of Military Stomatology and National Clinical Research Center for Oral Diseases and Shaanxi Clinical Research Center for Oral Diseases, Department of Orthodontics, School of Stomatology, The Fourth Military Medical University, Xi'an, China. Electronic address:
A 15-year-old female sought multidisciplinary treatment for hypodontia, three-dimensional problems, deep overbite, multiple occlusal interferences, and collapse of the occlusion. Through virtual-digital design with objective decomposition, this patient underwent five steps of orthodontic treatment under the guidelines of the principles: removal of occlusal restriction is a prerequisite; transverse problems are solved first; then sagittal problems; and vertical correction runs through the treatment. After orthodontic and prosthetic treatment, aesthetic appearance and functional occlusion were achieved.
View Article and Find Full Text PDFSpecial Issue on CDS Failures: A Case Study: Optimizing CDS for Pediatric Oncology Trials by Transitioning from Interruptive to Passive Alerts.
Appl Clin Inform
March 2025
Department of Pediatrics, Division of Pediatric Hematology/Oncology, The Hospital for Sick Children, Toronto, Canada.
Background: Many children with cancer are treated as part of interventional clinical trials. Ensuring that the correct chemotherapy treatment plan is used is paramount.
Objectives: The objectives of this report were to: (1) highlight the initial design of a clinical decision support (CDS) tool that was intended to help ensure the correct matching of research studies to research chemotherapy medications, (2) discuss the issues identified with the CDS tool, and (3) review the redesign of the tool that was done to overcome the issues identified.
Knee alignment and patella shape are not associated with persistence of patellofemoral pain.
J ISAKOS
March 2025
Erasmus Medical Center Rotterdam, Dr. Molewaterplein 40, 3015 GD Rotterdam. Electronic address:
Introduction: Patellofemoral pain (PFP) is suggested as a precursor of patellofemoral osteoarthritis (PFOA) later in life. This hypothesis is based on shared risk factors for both diseases, such as deviating alignment parameters. In patients with PFOA, certain 2D alignment parameters and 3D shape variations are associated with the progression of PFOA.
View Article and Find Full Text PDFUnplanned Return to the Operating Room After Cataract Surgery.
Am J Ophthalmol
March 2025
Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. Electronic address:
Objective: To determine the rate of unplanned return to operation room (OR) within 90 days of cataract surgery and to identify the most common pre-operative and intraoperative risk factors.
Design: Retrospective case-control study.
Subjects And Controls: Patients aged >= 40 years undergoing cataract surgery at the Wilmer Eye Institute between 2019-2022 with at least 90 days of postoperative follow-up were included.
Low-dose ferric carboxymaltose vs. oral iron for improving hemoglobin levels in postpartum East Asian women: A randomized controlled trial.
PLoS One
March 2025
Department of Obstetrics and Gynecology, The Jikei University School of Medicine, Tokyo, Japan.
Ferric carboxymaltose (FCM) is widely used to correct anemia and replenish iron stores rapidly, particularly in Western populations. However, lower doses of FCM are typically used in East Asia, with limited research on their effectiveness, especially in postpartum women. This randomized controlled trial aimed to assess the efficacy of low-dose FCM compared with oral ferrous sulfate in increasing postpartum hemoglobin (Hb) levels and replenishing iron stores in East Asian women.
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