Background: Metabolic bariatric surgery (MBS) candidates undergo a comprehensive nutritional preparation process by a registered dietitian (RD). The effect of eHealth interventions on the MBS preparation process is unknown.
Objectives: To assess the impact of adding an application to the nutritional preparation process on pre-surgery nutritional knowledge, physical, and behavioral parameters among MBS candidates.
Methods: An open-label randomized controlled trial among MBS candidates. All participants received 3-6 meetings with an RD and the intervention group also received access to an application containing information modules and a communication platform. Data was collected at baseline and end of preparation.
Results: Forty participants were recruited, of them 67.5% women, with a mean age and body mass index of 34 ± 10.1 years and 43.5 ± 6.0 kg/m, respectively. Nutritional knowledge, anthropometrics, functionality, adherence to most behavioral recommendations, and subjective state of health improved in both groups (P Time ≤ 0.044). Physical activity initiation (i.e., beginning of regular exercise engagement) was higher among the intervention group (40% at baseline and 68% at end of preparation vs 35% at baseline and 32% at end of preparation for interventions and controls, respectively, P Time × Group = 0.026). The application was rated as providing added value (8.2 on a scale of 1 (no added value) to 10 (meaningful added value)).
Conclusions: Nutrition preparation process with an RD improved MBS knowledge, adherence to behavioral recommendations, subjective state of health, and modestly enhanced weight and functionality outcomes among MBS candidates. Although rated as having an added value, incorporating an application had only a minimal impact on these outcomes.
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http://dx.doi.org/10.1007/s11695-025-07732-9 | DOI Listing |
J AOAC Int
March 2025
Department of Chemistry, Carleton University, 1125 Colonel By Drive, Ottawa, Ontario, K1S 5B6 Canada.
Background: Plant-based milk alternatives (PBMA) are increasingly popular due to rising lactose intolerance and environmental concerns over traditional dairy products. However, limited efforts have been made to develop rapid authentication methods to verify their biological origin.
Objective: In this study, we developed a rapid, on-site analytical method for the authentication and identification of PBMA made by six different plant species utilizing a portable Raman spectrometer coupled with machine learning.
J Org Chem
March 2025
Key Lab of Organic Optoelectronics & Molecular Engineering of Ministry of Education, Department of Chemistry, Tsinghua University, Beijing 100084, P. R. China.
Arylsulfonylindole and arylsulfenylindole motifs stand as privileged scaffolds in drug discovery. Traditional methods for synthesizing these molecules have relied mainly on prefunctionalized precursors, involving multistep processes and generating a large amount of waste. In this study, we present a modular protocol for the preparation of 3-sulfonylindoles and 3-sulfenylindoles using indoles and thiols as starting materials via hexamolybdate/HO-mediated oxidative dehydrogenative C-S coupling.
View Article and Find Full Text PDFACS Appl Mater Interfaces
March 2025
School of Chemistry and Environment, Changchun University of Science and Technology, Changchun 130022, China.
Doping guest materials into host materials with a confined space to suppress nonradiative decay is an effective strategy for achieving room-temperature phosphorescence (RTP). However, constructing host-guest doped materials with ultralong RTP (URTP) is still challenging. Herein, by embedding three coumarin derivatives into boric acid via one-step heat treatment, the URTP material with an afterglow lasting up to 60 s, a phosphorescence lifetime of 1.
View Article and Find Full Text PDFAnal Chem
March 2025
Department of Pharmaceutical Analysis, School of Pharmacy, Key Laboratory of Protection, Development and Utilization of Medicinal Resources in Liupanshan Area, Ministry of Education, Ningxia Medical University, Yinchuan 750004, China.
Biological aggregates play a crucial role in the pathogenesis of thrombotic diseases, especially thrombin-induced biological aggregates. Therefore, the efficient discovery of thrombin inhibitors is of great significance for the prevention and treatment of thrombotic diseases. In this study, the aggregation precursor protein fluorescent probe was successfully prepared for monitoring the production of biological aggregates induced by thrombin.
View Article and Find Full Text PDFPLoS One
March 2025
Medical School of Chinese PLA, Department of Plastic and Reconstructive Surgery, First Medical Center of Chinese PLA General Hospital, Beijing, China.
Diabetic wounds have a profound effect on both the physical and psychological health of patients, highlighting the urgent necessity for novel treatment strategies and materials. Macrophages are vital contributors to tissue repair mechanisms. Macrophage conditioned medium contains various proteins and cytokines related to wound healing, indicating its potential to improve recovery from diabetic wound.
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