Acute postinfarction ventricular septum defect has a persistently high mortality rate due to unstable scars in the acute phase, which make surgery or occluder use unsuitable. Delayed closure increases the risk of irreversible hemodynamic deterioration. To address this, a dual latex balloon catheter was designed for temporary closure and tested in a pig model. The catheter, with a 10 French profile and 80 cm in length, includes two independent latex balloons and an anticoagulant channel to prevent thrombus formation. It was inserted via the jugular vein and guided over a 0.014-inch wire to straddle and seal the ventricular septum defect. In eight Yorkshire pigs with ventricular septum defects and acute myocardial infarction, the catheter effectively closed defects ranging from 6.1 to 10.5 mm for two weeks without complications. This innovative tool shows promise as a bridge therapy for managing acute postinfarction ventricular septum defect and warrants further evaluation.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s12265-025-10601-6 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Evaluation of multiple ventricular septal defects using three-dimensional reconstruction models.
Eur J Cardiothorac Surg
March 2025
Department of Pediatrics, University of Toyama, Graduate School of Medicine, Toyama, Japan.
Objectives: Although there has been rapid development in the field of three-dimensional morphological analyses of congenital heart disease, with the three-dimensional volume-rendered images providing visualization of the external vascular anatomy, the precise reproduction of "Swiss-cheese" ventricular septum is not well established. We created three-dimensional printed models and computer graphics based on multi-slice computed tomography of patients with complex multiple ventricular septal defects for surgical decision planning of this difficult cardiac defect.
Methods: Seven patients with complex multiple ventricular septal defects were evaluated preoperatively using three-dimensional printed models and computer graphics to plan therapeutic interventions.
A Novel Dual Latex Balloon Catheter for Temporarily Closing Acute Postinfarction Ventricle Septum Defect (VSD) in a Pig Model.
J Cardiovasc Transl Res
March 2025
Department of Cardiology, The First Affiliated Hospital of Chongqing Medical University, No.1 Youyi Road, Yuzhong District, Chongqing, 400016, China.
Acute postinfarction ventricular septum defect has a persistently high mortality rate due to unstable scars in the acute phase, which make surgery or occluder use unsuitable. Delayed closure increases the risk of irreversible hemodynamic deterioration. To address this, a dual latex balloon catheter was designed for temporary closure and tested in a pig model.
View Article and Find Full Text PDFThe relationship between structures affecting maxillary sinus ventilation and maxillary sinus volume: a CT study.
Surg Radiol Anat
March 2025
Radiology Department, Faculty of Medicine, Necmettin Erbakan University, Konya, Turkey.
Purpose: This study aims to identify anatomical variations inside and outside the maxillary sinus (MS), determine their prevalence and coexistence, and investigate their relationship with MS volume in individuals without MS pathology, using ImFusion Suite software.
Methods: Analysis of 330 paranasal CT scans obtained from the radiology archive (2018-2021) was performed using the ImFusion Suite program. Anatomical variations, including accessory ostium, Haller cells, ethmomaxillary sinus, concha anomalies, septa, and impacted teeth, were identified and their frequency of coexistence was determined.
Split cord malformation - a simple, current classification based on CT and MRI neuroimaging studies.
Pol J Radiol
January 2025
Chair of Radiology, Faculty of Medicine, Jagiellonian University Medical College, Krakow, Poland.
The aim of this paper is to present the currently used classification of split cord malformation. Split cord malformation (SCM) is a developmental defect arising during neurulation, resulting in abnormal neural tube development, with the formation of a division within the spinal cord and dural sac. The terms diastematomyelia and diplomyelia are used in the literature to describe this defect.
View Article and Find Full Text PDFAnatomical Variations in Nasal Cavities and Paranasal Sinuses on Computed Tomography in Chronic Rhinosinusitis: Implications for Diagnosis and Treatment.
Indian J Otolaryngol Head Neck Surg
January 2025
Department of Radiology, Hue University of Medicine and Pharmacy, Hue University, Hue, Vietnam.
Chronic rhinosinusitis is a prevalent condition characterized by inflammation of the nasal and paranasal sinus cavities, significantly impacting quality of life and healthcare utilization. Computed tomography imaging is vital in assessing anatomical variations that may contribute to chronic rhinosinusitis pathogenesis. This study aimed to identify anatomical variations in the nasal cavities and paranasal sinuses using CT imaging and explore their relationship with sinus mucosal abnormalities.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!