A patient who had undergone radiation therapy for cancer developed a white coating on their tongue. This was initially misdiagnosed as a fungal infection, leading to unnecessary treatment. The actual cause was dry mouth, a common side effect of radiation therapy. This case highlights the importance of accurate diagnosis and appropriate management of oral health conditions, especially after medical treatments.
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http://dx.doi.org/10.1007/s13187-025-02579-1 | DOI Listing |
J Proteome Res
March 2025
Department of Radiation Oncology, The Ohio State University, Columbus, Ohio 43210, United States.
Lung cancer stands as the leading cause of cancer-related death worldwide, impacting both men and women in the United States and beyond. Radiation therapy (RT) serves as a key treatment modality for various lung malignancies. Our study aims to systematically assess the prognosis and influence of RT on metabolic reprogramming in patients diagnosed with nonsmall-cell lung cancer (NSCLC) through longitudinal metabolic profiling.
View Article and Find Full Text PDFSci Adv
March 2025
Department of Radiation Oncology, Harold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Lung cancer exhibits altered metabolism, influencing its response to radiation. To investigate the metabolic regulation of radiation response, we conducted a comprehensive, metabolic-wide CRISPR-Cas9 loss-of-function screen using radiation as selection pressure in human non-small cell lung cancer. Lipoylation emerged as a key metabolic target for radiosensitization, with lipoyltransferase 1 (LIPT1) identified as a top hit.
View Article and Find Full Text PDFJ Neurooncol
March 2025
Neuro-Oncology Unit, Davidoff Cancer Center, Rabin Medical Center- Beilinson Hospital, Petach Tikva, Israel.
Purpose: To evaluate short and long-term efficacy of bevacizumab (Bev), for the treatment of radiation necrosis (RN) in patients with brain metastasis after stereotactic radiosurgery (SRS).
Methods: The database of a tertiary medical center was reviewed for all adult patients treated by Bev (from January 2018 to January 2023) for RN after having received SRS for BM. Clinical and MRI data were systematically collected at baseline, immediately after the completion of Bev treatment, and at 6, 12, and, when available, 24 months post-treatment.
Radiol Med
March 2025
Radiotherapy and Radiosurgery Department, IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.
Aim: Despite the widespread use of immunotherapy (IO) and targeted therapy (TT) in clinical practice, data on toxicity in combination with SBRT are lacking, largely based on retrospective studies and case reports. The present survey, conducted within the AIRO Oligometastatic Study Group, was developed for radiation oncologists to investigate the current clinical practice in Italy regarding hypofractionated SBRT (defined as a dose/fraction ≥ 5 Gy) in cancer patients using IO and TT.
Methods: The online survey, composed of 19 questions, was developed using the cloud-based platform SurveyMonkey® and was sent to all registered AIRO members using the association's mailing list and was administered online and in anonymous form.
J Cancer Educ
March 2025
Département d´Odontologie, Faculté de Santé, Service d´Odontologie, Centre HospitalierUniversitaire, Université de Toulouse, 3 chemin des Maraîchers, Toulouse, 31400, France.
A patient who had undergone radiation therapy for cancer developed a white coating on their tongue. This was initially misdiagnosed as a fungal infection, leading to unnecessary treatment. The actual cause was dry mouth, a common side effect of radiation therapy.
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