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The causal relationships between inflammatory cytokines, blood metabolites, and thyroid cancer: a two-step Mendelian randomization analysis.
Discov Oncol
March 2025
Department of Thyroid Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Background: Thyroid cancer is a prevalent malignant tumor, especially with a higher incidence in women. Tumor microenvironment changes induced by inflammation and alterations in metabolic characteristics are critical in the development of thyroid cancer. Nevertheless, their causal relationships remain unclear.
View Article and Find Full Text PDFPosterior lumbar interbody fusion for degenerative spondylolisthesis; slippage reduction can be a risk factor for adjacent segment disease.
Eur J Orthop Surg Traumatol
March 2025
Nihon University School of Medicine, Itabashiku, Tokyo, Japan.
Purpose: Several risk factors for adjacent segment disease (ASD) after posterior lumbar interbody fusion (PLIF) have been reported. High pelvic incidence (PI) has been identified as risk factors for L4 anterior slip in cases of lumbar degenerative spondylolisthesis. Correcting the slip with L4-L5 fixation merely restores the lumbar alignment, but the PI itself remains unchanged.
View Article and Find Full Text PDFCorrection: Reduction of Lewy Body Pathology by Oral Cinnamon.
J Neuroimmune Pharmacol
March 2025
Department of Neurological Sciences, Rush University Medical Center, 1735 West Harrison St, Suite 310, Chicago, IL, 60612, USA.
Correction to: Development and external validation of a Nomogram to predict obstructive sleep apnea in Children.
Eur J Pediatr
March 2025
Department of Otorhinolaryngology Head and Neck Surgery, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Immunity and neuroinflammation in early stages of life and epilepsy.
Epilepsia
March 2025
Departamento de Neurologia e Neurocirurgia, Escola Paulista de Medicina, Universidade Federal de São Paulo (Unifesp), São Paulo, Brazil.
The immune system is crucial for the correct brain development, and recent findings also point toward central control of immune response. As the immune system is not fully developed at birth, the early years become an important window for infections and for the development of epilepsy. Both central and even peripheral inflammation may impact brain function, promoting opening of the blood-brain/blood and cerebrospinal barriers and allowing entry of immune cells and cytokines, which in turn may affect neuron function and connections.
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