Nanofluids have emerged as an advanced media in many applications, particularly thermal management and energy efficiency applications, with extensive research focusing on their thermophysical properties and thermal performances [...].
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Is There Polyamorphism in Amorphous Indomethacin? Investigating the Physicochemical Properties of Amorphous Indomethacin with Different Thermal History.
Mol Pharm
March 2025
Department of Pharmacy, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark.
Polyamorphism in organic molecules is a poorly understood and controversial phenomenon related to amorphous materials. Although very few studies, including our own, have demonstrated the existence of polyamorphism in drug molecules, this solid-state phenomenon is still very elusive and the investigation of its occurrence in other drugs is fundamental to understand its formation. Indomethacin (IND) has been recently discussed in the literature as a potential drug exhibiting polyamorphism.
View Article and Find Full Text PDFStructural modification of lactoferrin by epigallocatechin gallate: elucidation of its structure and exploration of its potential in promoting osteoblast proliferation.
Food Funct
March 2025
College of Food Science and Engineering, Nanjing University of Finance and Economics/Collaborative Innovation Center for Modern Grain Circulation and Safety, Nanjing 210023, China.
Lactoferrin (LF) and epigallocatechin gallate (EGCG) are recognized for their potent osteogenic properties. However, the osteogenic activity of LF-EGCG complexes is not fully understood. In this study, both non-covalent and covalent LF-EGCG complexes with different LF : EGCG ratios were prepared, and their effects on the LF structure and thermal stability were investigated using circular dichroism, Fourier transform infrared spectroscopy, fluorescence spectroscopy, Raman spectroscopy, and differential scanning calorimetry.
View Article and Find Full Text PDFEnhanced Tumor Ablation and Immune Activation Via Irreversible Electroporation and Functionalized Vermiculite Nanosheets.
Small
March 2025
State Key Laboratory of Advanced Medical Materials and Devices, Medical College, Tianjin University, Tianjin, 300072, China.
Irreversible electroporation (IRE) is a minimally invasive, non-thermal tumor ablation technique that induces nanoscale membrane perforation, leading to immunogenic cell death (ICD). However, IRE alone is limited by uneven electric field attenuation, incomplete tumor ablation, and the immunosuppressive nature of the tumor microenvironment. To address these challenges, a multifunctional nanomaterial, vermiculite nanosheets/calcium peroxide nanosheets (VMT/CaO NSs), is developed to enhance the efficacy of IRE.
View Article and Find Full Text PDFMacroscopically Self-Aligned and Chiralized Carbon Nanotubes: From Filtration to Innovation.
ACS Nano
March 2025
Department of Electrical and Computer Engineering, Rice University, 6100 Main Street, Houston,, Texas 77005, United States.
Because of their natural 1D structure combined with intricate chiral variations, carbon nanotubes (CNTs) exhibit various exceptional physical properties, such as ultrahigh thermal conductivity and diameter-dependent electrical behavior, ranging from semiconducting to metallic. While CNTs excel individually at the nanoscale, their 1D and chiral nature can be lost on a macroscopic scale when they are randomly assembled. Therefore, the alignment and organization of CNTs in macroscopic structures is crucial for harnessing their full potential.
View Article and Find Full Text PDFGreen Synthesis and Characterization of Silver Nanoparticles from Leaf Extract: Evaluation of Their Antioxidant, Anti-Inflammatory, Antibacterial, and Antibiofilm Efficacies.
Nanomaterials (Basel)
March 2025
Department of Biotechnology and Bioinformatics, Yogi Vemana University, Kadapa 516005, India.
The use of metal nanoparticles is gaining popularity owing to their low cost and high efficacy. We focused on green synthesis of silver nanoparticles (AgNPs) using (Tc) leaf extracts. The structural characteristics of Tc nanoparticles (TcAgNPs) were determined using several advanced techniques.
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