Alzheimer's disease refers to a neurological disorder marked by memory loss and cognitive dysfunction caused by the death of brain cells. It is a progressive, devitalizing disease of aging that has skyrocketed in recent years. The disease progresses gradually, with symptoms including forgetfulness, difficulty with language or communication, disorientation, mood swings, and changes in behaviour. Unani medicine, being an older system of medicine, does not mention Alzheimer's disease as such since the name was coined only in 1907 AD. The Unani medical literature has, however, described the existence of Nisyān with signs and symptoms similar to those of Alzheimer's disease. The renowned Unani scholars have not only mentioned the aetiology and pathogenesis of Nisyān but also designed a specific line of treatment. This study attempts to present the pathophysiology of Alzheimer's disease and Nisyān, along with an exploration of potential treatment options available in Unani medicine.
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