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Integrating manual therapy into headache management: bridging the evidence gap.
Neurol Sci
March 2025
Department of Biomedical and Neuromotor Sciences (DIBINEM), Alma Mater Studiorum University of Bologna, Via Zamboni 33, Bologna, 40126, Italy.
Manual therapy remains an underutilized yet promising complementary intervention for headache management. Despite growing evidence supporting its efficacy, it is often overshadowed by pharmacological approaches and other non-pharmacological treatments such as acupuncture. This article highlights the potential role of manual therapy in reducing headache frequency and intensity, particularly in tension-type headaches and migraine.
View Article and Find Full Text PDFHarnessing bee venom for inflammatory diseases management: from traditional medicine to nanotechnology.
Naunyn Schmiedebergs Arch Pharmacol
March 2025
Shoolini University of Biotechnology and Management Sciences, Solan, Himachal Pradesh, 173229, India.
This review investigates the anti-inflammatory potential of bee venom, a natural compound comprising peptides, enzymes, biogenic amines other bioactive amines, and other bioactive components. It aims to elucidate how bee venom mitigates inflammatory responses caused by tissue injury, infections, and trauma. This study also explores the advancements in nanotechnology to enhance bee venom's therapeutic effects.
View Article and Find Full Text PDFThe role of protein phosphorylation modifications mediated by iron metabolism regulatory networks in the pathogenesis of Alzheimer's disease.
Front Aging Neurosci
February 2025
Hospital of Encephalopathy, The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, China.
Alzheimer's disease (AD) is a severe neurodegenerative disease characterized mainly by the formation of amyloid beta (Aβ) plaques and abnormal phosphorylation of tau. In recent years, an imbalance in iron homeostasis has been recognized to play a key role in the pathological process of AD. Abnormal iron accumulation can activate various kinases such as glycogen synthase kinase-3β, cyclin-dependent kinase 5, and mitogen-activated protein kinase, leading to abnormal phosphorylation of tau and amyloid precursor protein, and accelerating the formation of Aβ plaques and neurofibrillary tangles.
View Article and Find Full Text PDFEffect of acupuncture in patients with postprandial distress syndrome: study protocol for a randomized controlled trial.
Front Med (Lausanne)
February 2025
School of Acupuncture-Moxibustion, Tuina and Rehabilitation, Hunan University of Chinese Medicine, Changsha, China.
Background: Postprandial distress syndrome (PDS) is the prominent subtype in patients with functional dyspepsia (FD) and currently lacks a satisfactory treatment. Acupuncture has become a promising alternative and complementary therapy for managing FD. However, high-level clinical evidence supporting the use of acupuncture for FD is limited.
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