Objectives: To identify implementation variables and justify the use of the community component of the Mental Health Gap Action Programme (mhGAP).
Method: The search was carried out in Cochrane, PubMed, Emerald, Scopus, Scielo, Redalyc and Google Scholar databases. Studies that analyzed the implementation of the community component of mhGAP were included, excluding those focused solely on the clinical component of mhGAP.
Results: Out of the 726 records initially identified, only four met the inclusion criteria. The findings reveal that the evaluation of the community component of mhGAP has primarily been conducted in conjunction with other global and community mental health strategies, as part of multimodal approaches. Factors are recognized as key barriers and facilitators for the successful implementation of the program.
Conclusion: The community component of mhGAP presents itself as a promising proposal to strengthen community-based mental health strategies. However, there is an urgent need to generate more evidence on the implementation of these strategies, particularly in terms of resource availability, long-term sustainability, and outcome monitoring.
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http://dx.doi.org/10.3389/phrs.2025.1607759 | DOI Listing |
J Am Coll Cardiol
March 2025
Ciccarone Center for Prevention of Cardiovascular Disease, Johns Hopkins Medicine, Baltimore, Maryland, USA; American Heart Association Tobacco Regulation and Addiction Center, Dallas, Texas, USA. Electronic address:
Background: Cigarette smoking is a strong risk factor for cardiovascular harm.
Objectives: The study sought to explore the detailed relationships between smoking intensity, pack-years, and time since cessation with inflammation, thrombosis, and subclinical atherosclerosis markers of cardiovascular harm.
Methods: We included 182,364 participants (mean age 58.
Handb Clin Neurol
March 2025
Language & Genetics Department, Max Planck Institute for Psycholinguistics, Nijmegen, The Netherlands; Department of Cognitive Neuroscience & Donders Community for Medical Neuroscience, Radboud University Medical Center, Nijmegen, The Netherlands. Electronic address:
Left-right asymmetry is an important aspect of human brain organization for functions including language and hand motor control, which can be altered in some psychiatric traits. The last 5 years have seen rapid advances in the identification of specific genes linked to variation in asymmetry of the human brain and/or handedness. These advances have been driven by a new generation of large-scale genome-wide association studies, carried out in samples ranging from roughly 16,000 to over 1.
View Article and Find Full Text PDFCold Spring Harb Protoc
March 2025
Department of Biology, Whitman College, Walla Walla, Washington 99362, USA
Synthetic biology approaches merge the tenets of engineering with established biological techniques to answer fundamental questions about living systems and to engineer biological forms and functions. Following the engineering principle of design-build-test-iterate, this review serves as a guide to applying synthetic principles and approaches in maize. We outline strategies for (1) choosing the optimal model organism to serve as a heterologous chassis for maize signaling pathways, (2) designing and building biological parts and devices to express pathway components, (3) choosing an analytical technique to measure pathway function, and (4) optimizing and troubleshooting the designed system.
View Article and Find Full Text PDFSci Total Environ
March 2025
SINTEF Ocean AS, Dept. Climate and Environment, Trondheim, Norway.
Seasonal dynamics can vastly influence the natural depletion of oil spilled into the ocean and the Arctic regions are characterized by large seasonal changes, especially in temperature and daylight. To determine the influences of seasonal variation on natural oil depletion processes like dissolution, photooxidation and biodegradation, we deployed thin films of three oils in natural seawater during the Arctic summer and winter in Svalbard, Norway. The extent of oil depletion varied with season and the type of the oil, however, considerable depletion of n-alkanes and polycyclic aromatic compounds were observed during both summer and winter.
View Article and Find Full Text PDFWaste Manag
March 2025
School of Environmental Studies, China University of Geosciences, Wuhan 430074, Hubei, China; Hubei Key Laboratory of Yangtze Catchment Environmental Aquatic Science, School of Environmental Studies, China University of Geosciences, Wuhan 430074, Hubei, China; National Engineering Research Center of Industrial Wastewater Detoxication and Resource Recovery, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China. Electronic address:
The safe disposal and utilization of bulk solid waste (SW) are critical challenges. Manufactured soil, a soil-like material composed of SW, offers a novel solution for resource recycling. However, the mechanisms underlying SW-based manufactured soil fertility development remain unclear.
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