To study the contribution of QRS prolongation to transplant-free survival, we conducted an observational study of 68 patients with sarcoidosis-related pulmonary hypertension. Every 10-ms increase in QRS interval was associated with an adjusted HR of 1.23 (95% CI: 1.06, 1.44) for the composite outcome of lung transplantation and all-cause mortality.
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http://dx.doi.org/10.1002/pul2.70021 | DOI Listing |
To study the contribution of QRS prolongation to transplant-free survival, we conducted an observational study of 68 patients with sarcoidosis-related pulmonary hypertension. Every 10-ms increase in QRS interval was associated with an adjusted HR of 1.23 (95% CI: 1.
View Article and Find Full Text PDFWorld J Cardiol
February 2025
Department of Cardiology, King George's Medical University, Lucknow 226003, Uttar Pradesh, India.
Cardiac resynchronization therapy (CRT) reduces heart failure (HF) hospitalizations and all-cause mortality in patients with HF with reduced ejection fraction with left bundle branch (LBB) block. Biventricular pacing (BVP) is considered the gold standard for achieving CRT; however, approximately 30%-40% of patients do not respond to BVP-CRT. Recent studies have demonstrated that LBB pacing (LBBP) produces remarkable results in CRT.
View Article and Find Full Text PDFCJC Open
February 2025
Barts Heart Centre, St Bartholomew's Hospital, London, UK.
Background: Cardiac resynchronization therapy (CRT) response relies on 2 factors: when and where to pace. These factors may be enhanced by dynamic atrioventricular delays (AVDs) (eg, SyncAV CRT, Abbott Cardiovascular, Abbott Park, IL) and multisite left ventricular (LV) pacing (eg, MultiPoint Pacing [MPP], Abbott). Their individual and combined synchronization contributions have not been evaluated across a comprehensive spectrum of pacing configurations.
View Article and Find Full Text PDFJ Toxicol Sci
March 2025
Emergency and Critical Care Center, Iizuka Hospital.
Prolongation of QRS duration (prolonged QRS) is associated with severe outcomes in non-tricyclic antidepressant poisoning. However, factors other than xenobiotics affecting QRS duration have not yet been investigated. Hence, this study aimed to identify factors contributing to prolonged QRS.
View Article and Find Full Text PDFJ Res Pharm Pract
December 2024
Department of Clinical Toxicology, Isfahan University of Medical Sciences, Isfahan, Iran.
Objective: Given the prevalence of methadone poisoning, this study was conducted to compare the cardiovascular complications following acute methadone poisoning in patients with and without a history of long-term methadone use.
Methods: In this retrospective study, information related to patients with acute methadone poisoning hospitalized at Al-Zahra and Khorshid hospitals in Isfahan-Iran was collected from hospital archives and analyzed. Patients were divided into two groups with and without a history of long-term methadone use.
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