In Romania, data pertaining to the incidence and prevalence of chronic kidney disease (CKD) are scant, with an even more limited understanding of the elderly demographic. In this study, we used a descriptive cross-sectional retrospective approach, drawing data from the Geriatrics and Gerontology Clinic at Dr. C.I. Parhon Clinical Hospital in Iași, Romania. We assessed renal function through creatinine measurements and estimated glomerular filtration rate (eGFR) computed using the CKD-Epidemiology Collaboration (EPI) 2021 equation. The final analysis incorporates 1080 patients, categorized based on their eGFR. The average age was 79.76 years. CKD stages 3a-5 prevalence was 25.03% (n=780) and CKD stages 1-5 was 34.6% (n=1080). The most prevalent stage was stage 3a with a frequency of 45% (n=486). Regarding age distribution, 26.2% (n=283) were young elderly, 52.1% (n=563) were elderly, and 21.6% (n=234) were old elderly, with CKD stage 3a prevalent in all age groups. This is the first study in Romania conducted exclusively on elderly patients with CKD. This study was conducted in a university center serving a population of 4.5 million patients, featuring a dedicated nephrology clinic. This study delves into the prevalence of CKD within the elderly demographic, examining its correlation with essential biomarkers of malnutrition. This study spans a decade, from 2012 to 2022, focusing on Romania's northeastern region, specifically Moldova. This is the second substantial analysis carried out in Romania and Eastern Europe, with a unique emphasis on patients aged 65 years and older.
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http://dx.doi.org/10.7759/cureus.80412 | DOI Listing |
Obesity (Silver Spring)
March 2025
Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Objective: The objective of this study was to evaluate associations of early-pregnancy plasma per- and polyfluoroalkyl substances (PFAS) with maternal post-pregnancy weight trajectory parameters.
Methods: We studied 1106 Project Viva participants with measures of early-pregnancy plasma concentrations of eight PFAS. We measured weight at in-person visits at 6 months and 3, 7, and 12 years after pregnancy and collected self-reported weight via annual questionnaires up to 17 years after pregnancy.
J Am Coll Cardiol
March 2025
Ciccarone Center for Prevention of Cardiovascular Disease, Johns Hopkins Medicine, Baltimore, Maryland, USA; American Heart Association Tobacco Regulation and Addiction Center, Dallas, Texas, USA. Electronic address:
Background: Cigarette smoking is a strong risk factor for cardiovascular harm.
Objectives: The study sought to explore the detailed relationships between smoking intensity, pack-years, and time since cessation with inflammation, thrombosis, and subclinical atherosclerosis markers of cardiovascular harm.
Methods: We included 182,364 participants (mean age 58.
J Am Coll Cardiol
March 2025
National Amyloidosis Centre, University College London, Royal Free Hospital, London, United Kingdom.
Background: Transthyretin amyloid cardiomyopathy (ATTR-CM) is an underdiagnosed chronic disease associated with progressive heart failure that results in impaired quality of life, repeated hospitalizations, and premature death. Acoramidis is a selective, oral transthyretin stabilizer recently approved by the U.S.
View Article and Find Full Text PDFEnviron Health Prev Med
March 2025
Department of Biostatistics, School of Public Health, Harbin Medical University.
Background: There is growing evidence that the occurrence and severity of respiratory diseases in children are related to the concentration of air pollutants. Nonetheless, evidence regarding the association between short-term exposure to air pollution and outpatient visits for respiratory diseases in children remains limited. Outpatients cover a wide range of disease severity, including both severe and mild cases, some of which may need to be transferred to inpatient treatment.
View Article and Find Full Text PDFZhong Nan Da Xue Xue Bao Yi Xue Ban
October 2024
Department of Pediatrics, Third Xiangya Hospital, Central South University, Changsha 410013.
Objectives: In the post-epidemic era, the prevalence of obesity among urban residents in China has risen sharply, with 34.8% of the population being overweight and 14.1% classified as obese.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!