The collapsibility and dynamic phenomenon of the upper airway in obstructive sleep apnea syndrome (OSAS) patients during sleep is a complex mechanism. Its assessment prior to definitive surgery by drug-induced sleep endoscopy may mimic a snap shot of airway collapse during natural sleep. However, it still presents a shortcoming even after three decades of research and evolution in its technique. The hypothetical concept is to perform an overnight objective assessment of the upper airway collapsibility by the acoustic reflection technique in OSAS patients to decide the appropriate management plan.
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http://dx.doi.org/10.1007/s12070-024-05265-8 | DOI Listing |
Ann Otol Rhinol Laryngol
March 2025
Departments of Otolaryngology & Sleep Medicine, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Objective: The apnea-hypopnea index (AHI) defines obstructive sleep apnea (OSA) severity but fails to describe nuances in disease burden. The modified sleep apnea severity index (mSASI) combines patient anatomy, weight, sleep study metrics, and symptoms to provide a composite OSA index ranging from 1 to 3. While prior studies have associated mSASI with quality of life and hypertension, its utility in continuous positive pressure intolerant (CPAPi) surgical patients remains unexplored.
View Article and Find Full Text PDFIndian J Otolaryngol Head Neck Surg
February 2025
Consultant Otolaryngology, Department of Otolaryngology-Head and Neck Surgery, NMC Specialty Hospital, Electra Street, Abu Dhabi, United Arab Emirates.
The collapsibility and dynamic phenomenon of the upper airway in obstructive sleep apnea syndrome (OSAS) patients during sleep is a complex mechanism. Its assessment prior to definitive surgery by drug-induced sleep endoscopy may mimic a snap shot of airway collapse during natural sleep. However, it still presents a shortcoming even after three decades of research and evolution in its technique.
View Article and Find Full Text PDFBMC Pulm Med
March 2025
Department of Respiratory and Critical Care Medicine, General Hospital of Ningxia Medical University, Yinchuan, China.
Background: Epidemiological investigations provide considerable evidence supporting the coexistence of upper airway ailments with lower airway disorders, but the association between common nasal diseases, such as allergic rhinitis, chronic sinusitis, nasal polyps, and chronic respiratory conditions require further exploration.
Methods: In this study, a two-sample mendelian randomization was employed to explore the potential association between allergic rhinitis, nasal polyps, and chronic sinusitis with various chronic respiratory diseases. For the primary analysis, summary statistics related to chronic respiratory diseases were obtained from the UK Biobank of European ancestry.
Physiol Rep
March 2025
Centre for Biological Timing and Cognition, Department of Cell & Systems Biology, University of Toronto, Toronto, Ontario, Canada.
The respiratory control system can exhibit neuronal plasticity following exposures to repetitive respiratory challenges. For example, repeated obstructive apneas can trigger a form of respiratory plasticity that results in the enhancement of inspiratory hypoglossal (XII) motoneuron activity. This increase in respiratory motor output is known as hypoglossal long-term facilitation (hLTF).
View Article and Find Full Text PDFOtolaryngol Head Neck Surg
March 2025
Department of Otolaryngology-Head and Neck Surgery, University of Kansas Medical Center, Kansas City, Kansas, USA.
Objective: The purpose of this study is to evaluate the long-term usage of the hypoglossal nerve stimulator and identify predictors of usage over time.
Study Design: Retrospective chart review.
Setting: Tertiary academic medical center and database.
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