This study aims to present a case of Sinonasal glomangiopericytoma (SNGPC) in a 43-year-old woman, emphasizing the diagnostic challenges and highlighting the importance of considering rare tumors in the differential diagnosis of nasal polyps. We describe the clinical presentation, diagnostic process, and treatment outcomes of a patient presenting with chronic bilateral nasal obstruction, anosmia, and intermittent epistaxis. Initial diagnosis of benign nasal polyps was made based on endoscopic findings, followed by histopathological analysis confirming bilateral SNGPC. Our case underscores the diagnostic challenges posed by SNGPC, its resemblance to benign nasal polyps, and the importance of meticulous evaluation and histopathological examination for accurate diagnosis. The patient underwent appropriate management, with successful confirmation and treatment of bilateral SNGPC. This case highlights the critical role of considering rare tumors in the differential diagnosis of nasal polyps. Early detection through continuous monitoring is essential for detecting potential recurrence or complications associated with SNGPC.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11890887 | PMC |
http://dx.doi.org/10.1007/s12070-024-05280-9 | DOI Listing |
Indian J Otolaryngol Head Neck Surg
February 2025
Division of Otolaryngology and Head and Neck Surgery, University of British Columbia, Vancouver, Canada.
Background: Recent studies have demonstrated that corticosteroid delivered by nasal irrigation is superior to nasal spray in the treatment of chronic rhinosinusitis patients who have undergone sinus surgery. However, the local cytotoxicity of both delivery methods has not been previously evaluated. In this study we aimed to evaluate the cytotoxicity of corticosteroid prepared nasal irrigation solution and commercially available corticosteroid nasal spray.
View Article and Find Full Text PDFIndian J Otolaryngol Head Neck Surg
February 2025
ENT and Neck and Head Surgery Department, University Medical Center Mohammed VI, Marrakech, Marrakech Morocco.
This study aims to present a case of Sinonasal glomangiopericytoma (SNGPC) in a 43-year-old woman, emphasizing the diagnostic challenges and highlighting the importance of considering rare tumors in the differential diagnosis of nasal polyps. We describe the clinical presentation, diagnostic process, and treatment outcomes of a patient presenting with chronic bilateral nasal obstruction, anosmia, and intermittent epistaxis. Initial diagnosis of benign nasal polyps was made based on endoscopic findings, followed by histopathological analysis confirming bilateral SNGPC.
View Article and Find Full Text PDFIndian J Otolaryngol Head Neck Surg
February 2025
Department of Pathology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka 576104 India.
Pituitary adenomas, the second most common intracranial pathology, often exhibit symptoms beyond the classic triad of headache, visual disturbances, and hormonal imbalances. Unusual presentations involve sinonasal pathology, cranial nerve involvement, and mass effects on adjacent structures like the skull base. Secretory adenomas may manifest hormonal changes and their effects.
View Article and Find Full Text PDFBMC Pulm Med
March 2025
Department of Respiratory and Critical Care Medicine, General Hospital of Ningxia Medical University, Yinchuan, China.
Background: Epidemiological investigations provide considerable evidence supporting the coexistence of upper airway ailments with lower airway disorders, but the association between common nasal diseases, such as allergic rhinitis, chronic sinusitis, nasal polyps, and chronic respiratory conditions require further exploration.
Methods: In this study, a two-sample mendelian randomization was employed to explore the potential association between allergic rhinitis, nasal polyps, and chronic sinusitis with various chronic respiratory diseases. For the primary analysis, summary statistics related to chronic respiratory diseases were obtained from the UK Biobank of European ancestry.
Immunol Res
March 2025
Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, Milan, Italy.
The epithelial barrier in different organs is the first line of defense against environmental insults and allergens, with type 2 immunity serving as a protective function. Genetic factors, and biological and chemical insults from the surrounding environment altered regulate epithelial homeostasis through disruption of epithelial tight junction proteins or dilated intercellular spaces. Recent studies suggest that epithelial barrier dysfunction contributes to pathologic alteration in diseases with type 2 immune dysregulation including (but not limited to) atopic dermatitis, prurigo nodularis, asthma, chronic rhinosinusitis with nasal polyps, and eosinophilic esophagitis.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!