Introduction: Mpox is a viral disease that primarily affects individuals living in endemic regions. The 2022 outbreak notably impacted HIV-positive individuals, who were disproportionately affected. This report describes the first confirmed case of Mpox in Burundi, involving an HIV-positive patient with advanced disease. The case was confirmed by the national laboratory during the early stages of the 2024 outbreak.
Case Presentation: A 50-year-old woman presented with pustular and necrotic skin lesions, vulval ulcers, and systemic symptoms. She was diagnosed with HIV upon initial evaluation and, despite an initial misdiagnosis, was ultimately confirmed to have a co-infection of Mpox. Complications included secondary bacterial infection, severe pain, and prolonged healing.
Conclusion: HIV coinfection can exacerbate Mpox, leading to severe clinical presentations. Therefore, early recognition and screening for HIV in Mpox patients are essential.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11894574 | PMC |
| http://dx.doi.org/10.3389/fmed.2025.1536774 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Cases of high-consequence infectious diseases identified in the UK, 1962-2023.
J Med Microbiol
March 2025
NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, UK.
The management of patients with acute infectious diseases can present significant challenges, especially if the causative agent has a propensity for person-to-person transmission. In such cases, effective patient management is dependent on both rapid identification of disease and the provision of necessary medical care while adhering to suitable infection prevention and control measures to reduce the potential for onwards transmission. The UK has operated a defined system for managing patients with high-consequence infectious diseases (HCIDs) since the 1970s, when protocols were first implemented following the first descriptions of several viral haemorrhagic fever diseases, including Marburg virus disease, Lassa fever and Ebola virus disease (EVD).
View Article and Find Full Text PDFCase report: The first case of Mpox in a patient with HIV in Burundi.
Front Med (Lausanne)
February 2025
Department of Dermatology, College of Health Sciences and Medicine, Bahir Dar University, Bahir Dar, Ethiopia.
Introduction: Mpox is a viral disease that primarily affects individuals living in endemic regions. The 2022 outbreak notably impacted HIV-positive individuals, who were disproportionately affected. This report describes the first confirmed case of Mpox in Burundi, involving an HIV-positive patient with advanced disease.
View Article and Find Full Text PDFEstablishment of a regional Mpox surveillance network in Central Africa: shared experiences in an endemic region.
Glob Health Res Policy
March 2025
Department of Epidemiology and Global Health, Institut National de Recherche Biomédicale (INRB), School of Medicine, University of Kinshasa (UNIKIN), Kinshasa, Democratic Republic of the Congo.
To address the underreporting of mpox cases in endemic regions, a regional surveillance network, known as the Mpox Threat Reduction Network (MPX-TRN), was established between five neighboring countries in Central and West Africa in 2022. One direct outcome of the MPX-TRN has been the strengthening of regional mpox surveillance. This consortium has facilited open communication channels, detection of cross-border mpox cases, and improvements of the detection and diagnosis of mpox in Central Africa and worldwide.
View Article and Find Full Text PDFMpox in a Patient With a Signal Transducer and Activator of Transcription 1 Gain-of-Function Mutation.
Mayo Clin Proc
March 2025
Division of Public Health, Infectious Diseases, and Occupational Medicine, Mayo Clinic, Rochester, MN.
We report a case of mpox in a patient with a signal transducer and activator of transcription 1 gain-of-function mutation. Despite initial improvement with intravenous immune globulin and tecovirimat, severe symptoms developed and the patient died. This underscores the need for immune system optimization and effective virucidal treatments for mpox.
View Article and Find Full Text PDFMpox awareness and vaccination willingness among a household cohort in Matlab, Bangladesh.
Trans R Soc Trop Med Hyg
February 2025
Laboratory of Food Safety and One Health, International Center for Diarrheal Disease Research, Dhaka 1212 Bangladesh.
Background: Awareness of mpox and acceptance of vaccinations are important components of a passive surveillance system and public health control efforts. We estimate and explore factors in awareness of mpox and acceptance of mpox vaccination in Matlab, a rural region of Bangladesh.
Methods: We conducted a cross-sectional survey in August and September 2022.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!