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Sepsis Resuscitation: Caution Against Conflating Initial Fluid Resuscitation and Overall Sepsis Management.
J Am Coll Emerg Physicians Open
April 2025
Department of Emergency Medicine, Kansas University Medical Center, Kansas City, Kansas, USA.
Dexmedetomidine administration is associated with reduced mortality in patients with sepsis-induced acute respiratory distress syndrome: a retrospective study.
BMC Anesthesiol
March 2025
Department of Emergency Medicine, Affiliated Hospital of Jiangsu University, Zhenjiang, 212001, Jiangsu, China.
Background: Although studies have revealed the benefits of using dexmedetomidine (DEX) in treating rodent models of acute lung injury (ALI) by improving their survival rates, clinical investigation on the effect of DEX on patients with acute respiratory distress syndrome (ARDS) remains scarce. Through this retrospective study, we aim to better understand the underlying mechanism of sepsis-induced ARDS and the effect of DEX on patients' standard treatment.
Methods: A total of 208 patients with sepsis-induced ARDS, admitted to the intensive care unit (ICU) at Affiliated Hospital of Jiangsu University, China, from January 2017 to December 2019, were included.
Septic shock upon admission to pediatric intensive care units: prognostic analysis of mortality in a retrospective cohort.
Bol Med Hosp Infant Mex
March 2025
School of Medicine, Universidad Peruana de Ciencias Aplicadas.
Background: Septic shock is a common cause of admission to pediatric intensive care units (PICU) and is associated with significant mortality. Our objective was to analyze the association between septic shock diagnosis at PICU admission and mortality during hospitalization.
Method: This retrospective cohort study was conducted in the PICU of Hospital Nacional Edgardo Rebagliati Martins (HNERM) in Lima, Peru, from January 2018 to December 2021.
Detection of hemodynamic changes in a porcine lipopolysaccharide model of systemic inflammation using dynamic light scattering measurements of the microcirculation.
Front Med (Lausanne)
February 2025
Department of Neonatal and Pediatric Intensive Care, Division of Neonatology, Erasmus MC Sophia Children's Hospital, University Medical Center Rotterdam, Rotterdam, Netherlands.
Background: The microcirculation is affected during sepsis, yet there is currently no clinically available technology for sepsis detection in the microcirculation. This study aimed to detect microcirculatory changes using a dynamic light scattering (DLS) skin sensor during an endotoxic shock with a systemic inflammatory response in a porcine lipopolysaccharide (LPS) model.
Methods: Thirty female Yorkshire x Norwegian Landrace pigs were divided into three groups: control, LPS, and LPS with resuscitation.
[Clinical characteristics and prognostic analysis of newly diagnosed acute myeloid leukemia with critical illness].
Zhonghua Xue Ye Xue Za Zhi
January 2025
National Clinical Research Center for Hematologic Diseases, the First Affiliated Hospital of Soochow University, Department of Hematology, Intensive Care Unit, Jiangsu Institute of Hematology, Suzhou 215006, China.
This study retrospectively analyzed the clinical characteristics of patients newly diagnosed with acute myeloid leukemia (AML) who were admitted to the hematology intensive care unit (HCU) with critical illness. It also examined factors associated with critical illness and early mortality in these patients. Clinical data were collected from 91 newly diagnosed AML patients admitted to the HCU of the Department of Hematology, First Affiliated Hospital of Soochow University, from October 2020 to 2024.
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