Background: Every day, nearly 830 women succumb to preventable pregnancy and childbirth-related complications, with 99 % of maternal deaths occurring in developing nations. Maternal mortality is disproportionately higher among women in rural areas and impoverished communities, especially in Sub-Saharan Africa, where approximately 85 % of cases are concentrated. In Somalia, a country grappling with prolonged conflicts and a healthcare system in disarray, maternal mortality remains alarmingly high at 692 per 100,000 live births. Delivery institutions in the IDP camps are mainly operated by humanitarian agencies and offer their services free of charge. We aim to investigate the prevalence of institutional delivery and factors associated with it among internally displaced mothers in Benadir region.
Methods: Community-based survey was conducted in ten Internally Displaced Persons (IDP) camps in the Benadir region of Somalia from September to October 2023. Questionnaires were administered to 410 women who had given birth in the last 6 months. Subsequent to data collection, a logistic regression analysis was performed to reveal associations between covariates of interest and the outcome variable.
Results: The study observed a 25 % prevalence of institutional delivery, with key associations identified. Women who were married during the data collection period had more than twice the odds of opting for healthcare facility deliveries (AOR 2.283, CI: 1.272-4.097), while employed women demonstrated nearly double the odds (AOR 1.916, CI: 1.109-3.312). Those who experienced their first pregnancy before the age of 20 had 1.7 times higher odds of delivering at a health facility (AOR 1.741, CI: 1.088-2.785). ANC attendees displayed over thirteen times the odds of choosing health facilities for delivery (AOR 13.299, CI: 6.752-26.196), and women knowledgeable about danger signs exhibited four times higher odds (AOR: 4.483, CI: 2.381-8.438). On the other hand, home deliveries are driven by various factors such as financial constraints, distant facility locations, urgent labor situations, lack of transportation, facility closures, a preference for the comfort of home, and fear of surgical procedures at health facilities.
Conclusion & Recommendation: The study highlights a troublingly low prevalence of institutional delivery compared with the national target, underscoring challenges in promoting healthcare facility utilization for childbirth. To improve rates, interventions should address socio-economic factors, emphasize healthcare benefits, and enhance community awareness of danger signs and antenatal care importance. Tackling access barriers, including financial constraints and facility distance, is pivotal in reducing the preference for home deliveries.
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http://dx.doi.org/10.1016/j.jmh.2025.100319 | DOI Listing |
Mol Pharm
March 2025
Department and Institute of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Positive surgical margins following radical prostatectomy significantly contribute to tumor recurrence. While systemic chemotherapy demonstrates limited efficacy in this context, local chemotherapy drug delivery systems based on nanomaterials offer promising strategies to address this issue by modifying drug release kinetics and distribution, thereby enhancing antitumor effects while minimizing the toxicities associated with systemic chemotherapy. In this study, we utilized electrospun nanofibrous mats loaded with docetaxel for sustained drug delivery.
View Article and Find Full Text PDFElife
March 2025
Machine Learning Core, National Institute of Mental Health, Bethesda, United States.
Fiber photometry has become a popular technique to measure neural activity in vivo, but common analysis strategies can reduce the detection of effects because they condense signals into summary measures, and discard trial-level information by averaging . We propose a novel photometry statistical framework based on functional linear mixed modeling, which enables hypothesis testing of variable effects at , and uses trial-level signals without averaging. This makes it possible to compare the timing and magnitude of signals across conditions while accounting for between-animal differences.
View Article and Find Full Text PDFJBRA Assist Reprod
March 2025
IVI Panama, Ciudad de Panama, Panama.
Research Question: What are the trends and impact of new technologies on the effectiveness and safety of assisted reproductive technology (ART) performed in Latin America during 2021?
Design: This was a retrospective collection of cycle-based multinational data obtained from ART procedures performed by 204 accredited institutions in 16 countries.
Results: In total 127,351 initiated cycles resulted in 20,032 deliveries and 22,708 births. ART utilization showed great variability, from 623.
J Pediatr Psychol
March 2025
Department of Education and Human Services, Lehigh University, Bethlehem, PA, USA.
Objective: Young children at-risk for attention-deficit/hyperactivity disorder (ADHD) often experience sleep problems, which may exacerbate ADHD symptoms and related impairment. Yet, little is known about modifiable factors associated with the maintenance of sleep problems. This study examined the relationships among parenting practices, behavioral self-regulation skills, and sleep functioning in young children at-risk for ADHD.
View Article and Find Full Text PDFHealth (London)
March 2025
Australian Research Centre in Sex, Health and Society, La Trobe University, Australia.
This article examines how drug education professionals understand and respond to the relationship between alcohol and other drug consumption, sex and harm. While recent research examines how these issues are addressed in drug education curriculum, little is known about the perspectives of professionals involved in education design and delivery. Research suggests that agency is centrally important for understanding experiences of harmful, pleasurable or ambiguous sexual encounters in consumption settings.
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