Introduction: Dengue fever, traditionally a tropical disease, has shown a notable increase in incidence within the United States over recent decades. This paper focuses on the increase in dengue fever cases in Maryland during increasing temperature and humidity and the expanding geographical range of Aedes mosquitoes, the primary vectors for dengue virus transmission.
Methods: Electronic health data was used to identify patterns in dengue incidence from 2014 to 2024. Correlation analysis between temperature and dengue incidence and a review of humidity factors was conducted.
Results: Results indicate an increased incidence of dengue fever cases over the past decade. However, a reduction in dengue incidence was observed in 2019-2020, likely due to COVID-19-related travel restrictions.
Discussion: As global temperatures increase, the habitats suitable for Aedes mosquitoes have expanded, allowing for their proliferation in previously inhospitable regions. Additionally, higher temperatures can accelerate the life cycle and viral replication rates in these mosquitoes, further enhancing transmission potential. Humidity, another key environmental factor, influences the life expectancy of dengue mosquitoes. This research underscores the urgency of addressing climate change as a public health issue, emphasizing the need for integrated vector management strategies and public health preparedness to mitigate the growing threat of dengue in temperate regions. By understanding the interplay between global warming, humidity, and dengue transmission, we can better inform policy decisions and healthcare practices to curb the spread of this disease in Maryland and the United States.
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http://dx.doi.org/10.3389/fepid.2025.1478425 | DOI Listing |
PLoS Negl Trop Dis
March 2025
Department of Pathogen Biology, Anhui Province Key Laboratory of Zoonoses, The Provincial Key Laboratory of Zoonoses of High Institutions in Anhui, School of Basic Medical Sciences, Anhui Medical University, Hefei, China.
Background: Dengue, the fastest-spreading vector-borne disease (VBD), significantly burdens global health systems. This study analyzed the trends in the global burden of dengue from 1990 to 2021, utilizing data from the Global Burden of Diseases, Injuries, and Risk Factors Study 2021 (GBD 2021).
Methodology/principal Findings: We retrieved data from GBD 2021 regarding dengue, including the number of incidences and age-standardized incidence rate (ASIR), the number of deaths and age-standardized death rate (ASDR), disability-adjusted life-years (DALYs) and age-standardized DALYs.
Cells
February 2025
Institute of Virology and Immunobiology, University of Würzburg, Versbacher Str. 7, 97078 Würzburg, Germany.
Cellular metabolism must adapt rapidly to environmental alterations and adjust nutrient uptake. Low glucose availability activates the AMP-dependent kinase (AMPK) pathway. We demonstrate that activation of AMPK or the downstream Unc-51-like autophagy-activating kinase (ULK1) inhibits receptor-mediated endocytosis.
View Article and Find Full Text PDFInfez Med
March 2025
Masters' Program of Clinical Epidemiology and Biostatistics, Faculty of Health Sciences, Universidad Cientifica del Sur, Lima, 15067, Peru.
Introduction: The incidence of dengue and its complications increases globally, mainly in areas where it is endemic; however, little literature evaluates outcomes in kidney transplant recipients (KTR). The present analysis aimed to determine the incidence, signs and symptoms, and allograft dysfunction in dengue-infected KTR.
Methods: Systematic review of the literature following PRISMA 2020 indications with studies included until November 24, 2023.
Introduction: Dengue is a mosquito-borne viral disease. It has been associated with high maternal and foetal morbidity and mortality. Therefore, this study aimed to describe the outcomes of Dengue infection in pregnant women in terms of maternal bleeding, miscarriage, preterm delivery, severe Dengue, Dengue shock and maternal mortality, as well as foetal outcomes in terms of foetal distress, low birth weight and neonatal mortality.
View Article and Find Full Text PDFFront Microbiol
February 2025
Laboratory of molecular studies of the Orinoquian region- LEMO, Facultad de Ciencias, Universidad Internacional del Trópico Americano, Universidad Internacional del Trópico Americano, Yopal, Colombia.
Studies focused on the epidemiological surveillance of arboviruses that cause potentially zoonotic diseases, such as dengue, Zika, or emerging viruses like West Nile virus (WNV), are critical due to their significant impact on public health. Although research on these infectious agents is increasing in Colombia, regions remain where the presence of zoonotic agents is still unknown. To address this knowledge gap, the present study aimed to investigate the current status of WNV circulation in wildlife in two municipalities of the department of Casanare (El Yopal and Paz de Ariporo) from the Colombian region of Orinoquia.
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