Various observations suggest a strong mental association between the physical and affective notion of warmth, possibly originating from early experiences with the parental figures. Behaviourally, this link could increase propensity to interact with, and bestow trust on, other individuals when prompted with warm primes. We investigated whether a similar phenomenon may follow the experience of coldness. Indeed, by evoking the idea of a rational, self-controlled person rather than that of an emotional one, the notion of 'cold' may elicit that of reliability, driving some individuals to behave more pro-socially in response to cold primes. To test this possibility, we collected a quantitative measure of the stereotypical 'warm=trustworthy' association from a sample of healthy volunteers (Exp1, N=50) and verified whether variability in this parameter predicts behavioural responses to thermal primes in an Investment Game (Exp2, N=32). An implicit link between qualities denoting trustworthiness and physical coldness (rather than warmth) did emerge in some participants. This variability affected responses at the Investment Game, confirming that intervening factors influence how bodily experiences translate into cognition. To further investigate the role of experience, linguistic and cultural factors, we compared responses to warm/cold primes of a thermally deafferented participant and healthy volunteers (Exp3, N=20). Her behaviour confirmed that incidental sensory information does not affect all individuals in the same way: previous knowledge and individual experience contribute to shaping the mental association between the physical and the affective notion of warmth/coldness. These findings provide novel insight into research on embodied processes relative to social concepts.
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http://dx.doi.org/10.1177/17470218251329230 | DOI Listing |
Blood
March 2025
Vanderbilt UniversityVanderbilt-Meharry Center of Excellence in Sickle Cell Disease, Nashville, Tennessee, United States.
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Faculty of Education, Mie University, Mie, Japan.
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Wood College of Osteopathic Medicine, Marian University, Indianapolis, IN, USA.
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Genentech, Inc, South San Francisco, CA, United States.
A gene encoding the transcription factor RTF1 has been associated with an increased risk of ulcerative colitis (UC). In this study, we investigated its function in modulating T cells expressing interleukin-17A (Th17 cells), a cardinal cell type promoting intestinal inflammation. Our results indicate that Rtf1 deficiency disrupts the differentiation of Th17 cells, while leaving regulatory T cells (Treg) unaffected.
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The relationship between sleep deprivation, obesity, and systemic inflammation is a critical area of investigation due to its significant impact on health. While it is established that poor sleep adversely affects obesity and metabolic syndromes, the specific mechanisms, particularly subclinical inflammation independent of obesity, remain unclear. This study investigates how sleep quality influences monocyte subclass distribution and its association with systemic inflammation across a spectrum of body mass index categories.
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