Evidence-based medicine (EBM) enhances clinical decision-making but faces implementation challenges, particularly in dentistry, where patient-specific complexities limit its effectiveness. This article examines EBM through the lens of Aristotelian logic, exploring its use of deductive and inductive reasoning and its limitations in addressing real-world variability. We then discuss how artificial intelligence (AI) can enhance EBM by synthesizing data, automating evidence appraisal, and generating personalized treatment insights. While AI offers a promising solution, it also presents challenges related to ethics, transparency, and reliability. Integrating AI into EBM requires careful consideration to ensure precise, adaptive, and patient-centered decision-making.Knowledge Transfer Statement:This commentary provides a critical discourse on the challenges of evidence-based medicine and how artificial intelligence could help address these shortcomings.
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http://dx.doi.org/10.1177/23800844251321839 | DOI Listing |
JMIR Med Inform
March 2025
LynxCare Inc, Leuven, Belgium.
Background: Processing data from electronic health records (EHRs) to build research-grade databases is a lengthy and expensive process. Modern arthroplasty practice commonly uses multiple sites of care, including clinics and ambulatory care centers. However, most private data systems prevent obtaining usable insights for clinical practice.
View Article and Find Full Text PDFJMIR Med Inform
March 2025
Department of Emergency and Critical Care Medicine, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuo, Chiba, 260-8677, Japan, 81 432262372.
This study demonstrated that while GPT-4 Turbo had superior specificity when compared to GPT-3.5 Turbo (0.98 vs 0.
View Article and Find Full Text PDFJ Med Internet Res
March 2025
Westmead Applied Research Centre, Faculty of Medicine and Health, The University of Sydney, Westmead, Australia.
Background: Conversational artificial intelligence (AI) allows for engaging interactions, however, its acceptability, barriers, and enablers to support patients with atrial fibrillation (AF) are unknown.
Objective: This work stems from the Coordinating Health care with AI-supported Technology for patients with AF (CHAT-AF) trial and aims to explore patient perspectives on receiving support from a conversational AI support program.
Methods: Patients with AF recruited for a randomized controlled trial who received the intervention were approached for semistructured interviews using purposive sampling.
JMIR Res Protoc
March 2025
Institute for Data Science and Informatics, University of Missouri, Columbia, MO, United States.
Background: Amyotrophic lateral sclerosis (ALS) leads to rapid physiological and functional decline before causing untimely death. Current best-practice approaches to interdisciplinary care are unable to provide adequate monitoring of patients' health. Passive in-home sensor systems enable 24×7 health monitoring.
View Article and Find Full Text PDFOncotarget
March 2025
Worldwide Innovative Network (WIN) Association - WIN Consortium, Chevilly-Larue, France.
The human genome project ushered in a genomic medicine era that was largely unimaginable three decades ago. Discoveries of druggable cancer drivers enabled biomarker-driven gene- and immune-targeted therapy and transformed cancer treatment. Minimizing treatment not expected to benefit, and toxicity-including financial and time-are important goals of modern oncology.
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