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Background And Aims: Alzheimer's disease (AD) is a widespread neurodegenerative condition that has a growing impact on a global scale. This study aims to examine the relationship between cerebral blood flow (CBF) and the synaptic biomarker growth-associated protein 43 (GAP-43) through the utilization of arterial spin labeling (ASL). The research identified noteworthy correlations between cerebrospinal fluid (CSF) GAP-43 levels, CBF, and cognitive composite scores, especially among participants with mild cognitive impairment (MCI) who possess the APOE-ε4 gene.
View Article and Find Full Text PDFHuman Milk Oligosaccharides in Breast Milk at Two Weeks of Age in Relation to Neurodevelopment in 2-Year-Old Children Born Extremely Preterm: An Explorative Trial.
Nutrients
February 2025
Division of Children's and Women's Health, Department of Biomedical and Clinical Sciences, Linköping University, 581 83 Linköping, Sweden.
Preventing neurodevelopmental impairment after extremely preterm birth remains challenging. While breast milk feeding is linked to better neurodevelopment, the underlying mechanisms are unclear. This study explored the association between individual human milk oligosaccharides (HMO) and neurodevelopment at two years of age in extremely preterm children.
View Article and Find Full Text PDFGrowth Rate Determination of in Ready-To-Eat Fish Products Under Different Storage Conditions for Possible Shelf-Life Extension.
Foods
February 2025
Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna "Bruno Ubertini", 25124 Brescia, Italy.
An increasing trend among food business operators (FBOs) to extend the shelf life of Ready-To-Eat (RTE) fish products over 5 days, the duration usually assigned to this kind of product, has been observed recently. In this study, three independent challenge tests (food artificial contamination) were performed on tuna fillet, marinated salmon tartare, and cubed salmon, with the aim of calculating the maximum growth rate (V) of and estimating the time required to reach the legal limit of 2 log CFU/g, as established by European Regulation 2073/2005. The pathogen counts were fitted by the model of Baranyi and Roberts to calculate the V, which were 0.
View Article and Find Full Text PDFCorrection: Han et al. Genotypic Homogeneity in Distinctive Transforming Growth Factor-Beta-Induced (TGFBI) Protein Phenotypes. 2021, , 1230.
Int J Mol Sci
March 2025
Singapore National Eye Centre, Singapore 168751, Singapore.
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