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Computerized adaptive resting with the I-HaND scale for monitoring patients with upper limb nerve pathology.

J Hand Surg Eur Vol

March 2025

1. Authorship: The authors are Mary Rose Harvey, Conrad Harrison and the Working group for computerised adaptive testing of the I-HaND. Underneath the main authors, the working group members should be listed as: Ryckie G Wade, Jeremy Rodrigues, Christina Jerosch-Herold, Caroline Miller, Christopher McGhee, Grainne Bourke, Chiraag Karia, Alna Dony, Dominic Power, Mark Ashwood.

The Impact of Hand Nerve Disorders scale is a patient-reported outcome measure for upper limb nerve pathology. We aimed to assess its structural validity using item response theory and to develop computerized adaptive testing algorithms. We conducted a series of psychometric studies to assess constructs measured, applied an item response theory model to the data, then developed computerized adaptive testing algorithms.

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Aim(s): To investigate the impact of the absence of specific advice for oral fluid intake, compared to supplementation water intake on the occurrence of post-dural puncture headache.

Design: A prospective, open-label, non-inferiority, multicenter trial including hospitalized patients requiring a diagnostic lumbar puncture in seven hospitals in France.

Methods: Patients were randomly allocated (1:1) either to receive no specific advice on oral fluid intake (FREE-FLUID), or to be encouraged to drink 2 liters of water (CONTROL) within the 2 hours after lumbar puncture.

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Objectives: Our overall aim was to develop a smartphone app to collect photographic images of Raynaud's phenomenon (RP) attacks alongside patient reported outcome measures (PROMs). Specific objectives included assessing the feasibility of patients documenting RP attacks using mobile phones, developing image analysis methods to document colour change, and comparing photographic parameters to 'non-imaging' app and paper diary parameters.

Methods: Study 1: 36 patients with systemic sclerosis (SSc)-related RP photographed RP attacks over 15 days as well as completing an RP paper diary.

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Psychometric validation of the Chronic Ocular Pain Questionnaire (COP-Q).

J Patient Rep Outcomes

March 2025

Department of Ophthalmology, Cornea Service, New England Eye Center and Tufts Medical Center, Tufts University School of Medicine, Boston, MA, USA.

Background: The Chronic Ocular Pain Questionnaire (COP-Q) is a newly developed patient-reported outcome (PRO) measure intended to assess symptoms and impacts associated with Chronic Ocular Surface Pain (COSP). This study assessed the psychometric properties of the COP-Q to determine the adequacy of the COP-Q as a 'fit-for-purpose' instrument to derive trial endpoints for future clinical studies in COSP.

Methods: Patients with COSP completed the COP-Q daily for four weeks on an electronic, touch-screen, tablet device as part of a longitudinal, observational study in the United States (N = 124).

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Background: Multimodal neuromonitoring (MMM) aids early detection of secondary brain injury in neurointensive care and facilitates research in pathophysiologic mechanisms of the injured brain. Invasive ICP monitoring has been the gold standard for decades, however additional methods exist (aMMM). It was hypothesized that local practices regarding aMMM vary considerably and that inter-and intracenter consensus is low.

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