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http://dx.doi.org/10.1186/s40364-025-00761-7 | DOI Listing |
Biomark Res
March 2025
The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, 510260, China.
Sci Rep
June 2024
Department of Pulmonary Surgery, Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, China.
J Cancer Res Clin Oncol
March 2024
Department of Stomatology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, Anhui, China.
Background: Head and neck squamous cell carcinoma (HNSCC) is a significant health concern with a variable global incidence and is linked to regional lifestyle factors and HPV infections. Despite treatment advances, patient prognosis remains variable, necessitating an understanding of its molecular mechanisms and the identification of reliable prognostic biomarkers.
Methods: We analyzed 959 HNSCC samples and employed batch correction to obtain consistent transcriptomic data across cohorts.
Carcinogenesis
April 2024
Department of Experimental Research, Guangxi Medical University Cancer Hospital, Nanning 530021, China.
Disulfidptosis is a novel form of programmed cell death involved in migration and invasion of cancer cells, but few studies investigated the roles of genetic variants in disulfidptosis-related genes in survival of patients with hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC). We used Cox proportional hazards regression analyses, Kaplan-Meier curves and receiver operating characteristic curves to assess effects of genetic variants in 14 disulfidptosis-related genes on overall survival of 866 HBV-HCC patients. The Bayesian false discovery probability was used for multiple testing corrections.
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